ENSG00000115687


Homo sapiens

Features
Gene ID: ENSG00000115687
  
Biological name :PASK
  
Synonyms : PAS domain containing serine/threonine kinase / PASK / Q96RG2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q37.3
Gene start: 241106099
Gene end: 241150264
  
Corresponding Affymetrix probe sets: 206594_at (Human Genome U133 Plus 2.0 Array)   213534_s_at (Human Genome U133 Plus 2.0 Array)   216945_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408506
Ensembl peptide - ENSP00000400734
Ensembl peptide - ENSP00000441374
Ensembl peptide - ENSP00000486149
Ensembl peptide - ENSP00000234040
Ensembl peptide - ENSP00000351475
Ensembl peptide - ENSP00000384016
Ensembl peptide - ENSP00000384438
Ensembl peptide - ENSP00000395672
Ensembl peptide - ENSP00000397922
NCBI entrez gene - 23178     See in Manteia.
OMIM - 607505
RefSeq - XM_017003636
RefSeq - XM_005246991
RefSeq - XM_011510826
RefSeq - XM_011510828
RefSeq - XM_011510829
RefSeq - XM_011510830
RefSeq - XM_011510831
RefSeq - XM_011510832
RefSeq - XM_011510833
RefSeq - XM_017003634
RefSeq - XM_017003635
RefSeq - NM_001252119
RefSeq - NM_001252120
RefSeq - NM_001252122
RefSeq - NM_001252124
RefSeq - NM_015148
RefSeq Peptide - NP_001239049
RefSeq Peptide - NP_001239051
RefSeq Peptide - NP_001239053
RefSeq Peptide - NP_055963
RefSeq Peptide - NP_001239048
swissprot - C9J4R3
swissprot - F8WEB4
swissprot - H7C0L7
swissprot - Q96RG2
swissprot - C9J1Z3
Ensembl - ENSG00000115687
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paskENSDARG00000075008Danio rerio
 PASKENSGALG00000006016Gallus gallus
 PaskENSMUSG00000026274Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIM1 / P11309 / Pim-1 proto-oncogene, serine/threonine kinaseENSG000001371938
PIM3 / Q86V86 / Pim-3 proto-oncogene, serine/threonine kinaseENSG000001983558
PIM2 / Q9P1W9 / Pim-2 proto-oncogene, serine/threonine kinaseENSG000001020968


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR035965  PAS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043576 regulation of respiratory gaseous exchange ISS
 biological_processGO:0045719 negative regulation of glycogen biosynthetic process IDA
 biological_processGO:0045727 positive regulation of translation TAS
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0070092 regulation of glucagon secretion ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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