ENSG00000198355


Homo sapiens

Features
Gene ID: ENSG00000198355
  
Biological name :PIM3
  
Synonyms : PIM3 / Pim-3 proto-oncogene, serine/threonine kinase / Q86V86
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.33
Gene start: 49960513
Gene end: 49964080
  
Corresponding Affymetrix probe sets: 224739_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000353824
NCBI entrez gene - 415116     See in Manteia.
OMIM - 610580
RefSeq - NM_001001852
RefSeq Peptide - NP_001001852
swissprot - Q86V86
Ensembl - ENSG00000198355
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pim3ENSDARG00000055129Danio rerio
 PIM3ENSGALG00000023576Gallus gallus
 Pim3ENSMUSG00000035828Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIM1 / P11309 / Pim-1 proto-oncogene, serine/threonine kinaseENSG0000013719367
PIM2 / Q9P1W9 / Pim-2 proto-oncogene, serine/threonine kinaseENSG0000010209656
PASK / Q96RG2 / PAS domain containing serine/threonine kinaseENSG0000011568733


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017348  Serine/threonine-protein kinase pim-1/2/3
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0046777 protein autophosphorylation IBA
 biological_processGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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