ENSG00000103310


Homo sapiens

Features
Gene ID: ENSG00000103310
  
Biological name :ZP2
  
Synonyms : Q05996 / zona pellucida glycoprotein 2 / ZP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.2
Gene start: 21197450
Gene end: 21214510
  
Corresponding Affymetrix probe sets: 207933_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458991
Ensembl peptide - ENSP00000460971
NCBI entrez gene - 7783     See in Manteia.
OMIM - 182888
RefSeq - XM_011545942
RefSeq - NM_001290104
RefSeq - NM_003460
RefSeq Peptide - NP_003451
RefSeq Peptide - NP_001277033
swissprot - Q05996
Ensembl - ENSG00000103310
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-223m11.2ENSDARG00000017188Danio rerio
 si:dkey-19b23.11ENSDARG00000079034Danio rerio
 si:dkeyp-50f7.2ENSDARG00000069251Danio rerio
 ZP2ENSGALG00000002428Gallus gallus
 Zp2ENSMUSG00000030911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZP4 / Q12836 / zona pellucida glycoprotein 4ENSG0000011699621
ZP1 / P60852 / zona pellucida glycoprotein 1ENSG0000014950617


Protein motifs (from Interpro)
Interpro ID Name
 IPR001507  Zona pellucida domain
 IPR017977  Zona pellucida domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0060468 prevention of polyspermy ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005771 multivesicular body IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015026 coreceptor activity TAS
 molecular_functionGO:0032190 acrosin binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Interaction With The Zona Pellucida


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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