ENSG00000104142


Homo sapiens

Features
Gene ID: ENSG00000104142
  
Biological name :VPS18
  
Synonyms : Q9P253 / VPS18 / VPS18, CORVET/HOPS core subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q15.1
Gene start: 40894430
Gene end: 40903975
  
Corresponding Affymetrix probe sets: 1552276_a_at (Human Genome U133 Plus 2.0 Array)   223346_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453555
Ensembl peptide - ENSP00000220509
Ensembl peptide - ENSP00000453265
NCBI entrez gene - 57617     See in Manteia.
OMIM - 608551
RefSeq - XM_017022447
RefSeq - NM_020857
RefSeq - XM_011521844
RefSeq Peptide - NP_065908
swissprot - A0A024R9R3
swissprot - Q9P253
swissprot - H0YLM6
swissprot - H0YMC9
Ensembl - ENSG00000104142
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps18ENSDARG00000070433Danio rerio
 VPS18ENSGALG00000008496Gallus gallus
 Vps18ENSMUSG00000034216Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000547  Clathrin, heavy chain/VPS, 7-fold repeat
 IPR007810  Pep3/Vps18/deep orange
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007032 endosome organization IDA
 biological_processGO:0007040 lysosome organization IDA
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0035542 regulation of SNARE complex assembly IBA
 biological_processGO:0046718 viral entry into host cell IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030897 HOPS complex IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0033263 CORVET complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding IDA
 molecular_functionGO:0030674 protein binding, bridging IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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