ENSG00000104852


Homo sapiens

Features
Gene ID: ENSG00000104852
  
Biological name :SNRNP70
  
Synonyms : P08621 / small nuclear ribonucleoprotein U1 subunit 70 / SNRNP70
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.33
Gene start: 49085419
Gene end: 49108605
  
Corresponding Affymetrix probe sets: 201221_s_at (Human Genome U133 Plus 2.0 Array)   213121_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000470023
Ensembl peptide - ENSP00000471006
Ensembl peptide - ENSP00000472998
Ensembl peptide - ENSP00000221448
Ensembl peptide - ENSP00000385077
Ensembl peptide - ENSP00000468828
Ensembl peptide - ENSP00000468952
NCBI entrez gene - 6625     See in Manteia.
OMIM - 180740
RefSeq - NM_003089
RefSeq - NM_001301069
RefSeq Peptide - NP_001287998
RefSeq Peptide - NP_003080
swissprot - P08621
swissprot - M0QX04
swissprot - M0QYR1
swissprot - A0A024QZD5
Ensembl - ENSG00000104852
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snrnp70ENSDARG00000077126Danio rerio
 Q62376ENSMUSG00000063511Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q16560 / SNRNP35 / small nuclear ribonucleoprotein U11/U12 subunit 35ENSG0000018420923


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR022023  U1 small nuclear ribonucleoprotein of 70kDa N-terminal
 IPR034143  snRNP70, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IC
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0043462 regulation of ATPase activity TAS
 biological_processGO:0043484 regulation of RNA splicing IMP
 biological_processGO:0048026 positive regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:0061084 negative regulation of protein refolding TAS
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:1904715 negative regulation of chaperone-mediated autophagy TAS
 cellular_componentGO:0000243 commitment complex IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IDA
 cellular_componentGO:0005685 U1 snRNP IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071004 U2-type prespliceosome IBA
 cellular_componentGO:0071011 precatalytic spliceosome IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030619 U1 snRNA binding IBA
 molecular_functionGO:1990446 U1 snRNP binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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