ENSG00000105366


Homo sapiens

Features
Gene ID: ENSG00000105366
  
Biological name :SIGLEC8
  
Synonyms : Q9NYZ4 / sialic acid binding Ig like lectin 8 / SIGLEC8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51450847
Gene end: 51458456
  
Corresponding Affymetrix probe sets: 208253_at (Human Genome U133 Plus 2.0 Array)   216327_s_at (Human Genome U133 Plus 2.0 Array)   216328_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321077
Ensembl peptide - ENSP00000389142
Ensembl peptide - ENSP00000339448
NCBI entrez gene - 27181     See in Manteia.
OMIM - 605639
RefSeq - XM_011526734
RefSeq - NM_014442
RefSeq - XM_011526735
RefSeq Peptide - NP_055257
swissprot - Q9NYZ4
swissprot - C9JT30
Ensembl - ENSG00000105366
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio
 Q91Y57ENSMUSG00000030474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y286 / SIGLEC7 / sialic acid binding Ig like lectin 7ENSG0000016899568
Q96PQ1 / SIGLEC12 / sialic acid binding Ig like lectin 12 (gene/pseudogene)ENSG0000025452168
Q9Y336 / SIGLEC9 / sialic acid binding Ig like lectin 9ENSG0000012945060
O43699 / SIGLEC6 / sialic acid binding Ig like lectin 6ENSG0000010549246
O15389 / SIGLEC5 / sialic acid binding Ig like lectin 5ENSG0000010550146
AC018755.2ENSG0000026850046
Q96RL6 / SIGLEC11 / sialic acid binding Ig like lectin 11ENSG0000016164043
Q96LC7 / SIGLEC10 / sialic acid binding Ig like lectin 10ENSG0000014251242
Q08ET2 / SIGLEC14 / sialic acid binding Ig like lectin 14ENSG0000025441540
CD33 / P20138 / CD33 moleculeENSG0000010538340
MAG / P20916 / myelin associated glycoproteinENSG0000010569522
AC011452.1ENSG000002691790


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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