ENSG00000105492


Homo sapiens

Features
Gene ID: ENSG00000105492
  
Biological name :SIGLEC6
  
Synonyms : O43699 / sialic acid binding Ig like lectin 6 / SIGLEC6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51519525
Gene end: 51531856
  
Corresponding Affymetrix probe sets: 206519_x_at (Human Genome U133 Plus 2.0 Array)   206520_x_at (Human Genome U133 Plus 2.0 Array)   210796_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401502
Ensembl peptide - ENSP00000375674
Ensembl peptide - ENSP00000410679
Ensembl peptide - ENSP00000344064
Ensembl peptide - ENSP00000345907
Ensembl peptide - ENSP00000353071
NCBI entrez gene - 946     See in Manteia.
OMIM - 604405
RefSeq - XM_017027511
RefSeq - NM_001177547
RefSeq - NM_001177548
RefSeq - NM_001177549
RefSeq - NM_001245
RefSeq - NM_198845
RefSeq - NM_198846
RefSeq - XM_011527533
RefSeq - XM_011527534
RefSeq - XM_011527535
RefSeq - XM_011527536
RefSeq - XM_011527537
RefSeq - XM_011527538
RefSeq - XM_011527539
RefSeq Peptide - NP_942143
RefSeq Peptide - NP_001171018
RefSeq Peptide - NP_001171019
RefSeq Peptide - NP_001171020
RefSeq Peptide - NP_001236
RefSeq Peptide - NP_942142
swissprot - O43699
swissprot - A0A024R4K4
Ensembl - ENSG00000105492
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96PQ1 / SIGLEC12 / sialic acid binding Ig like lectin 12 (gene/pseudogene)ENSG0000025452151
Q9Y286 / SIGLEC7 / sialic acid binding Ig like lectin 7ENSG0000016899551
Q9NYZ4 / SIGLEC8 / sialic acid binding Ig like lectin 8ENSG0000010536651
AC018755.2ENSG0000026850050
O15389 / SIGLEC5 / sialic acid binding Ig like lectin 5ENSG0000010550150
Q9Y336 / SIGLEC9 / sialic acid binding Ig like lectin 9ENSG0000012945047
CD33 / P20138 / CD33 moleculeENSG0000010538346
Q96LC7 / SIGLEC10 / sialic acid binding Ig like lectin 10ENSG0000014251241
Q96RL6 / SIGLEC11 / sialic acid binding Ig like lectin 11ENSG0000016164040
Q08ET2 / SIGLEC14 / sialic acid binding Ig like lectin 14ENSG0000025441539
MAG / P20916 / myelin associated glycoproteinENSG0000010569522
AC011452.1ENSG000002691790


Protein motifs (from Interpro)
Interpro ID Name
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007267 cell-cell signaling TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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