ENSG00000254415


Homo sapiens

Features
Gene ID: ENSG00000254415
  
Biological name :SIGLEC14
  
Synonyms : Q08ET2 / sialic acid binding Ig like lectin 14 / SIGLEC14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51642553
Gene end: 51646801
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000354090
NCBI entrez gene - 100049587     See in Manteia.
RefSeq - NM_001098612
RefSeq - XM_017026113
RefSeq Peptide - NP_001092082
swissprot - Q08ET2
Ensembl - ENSG00000254415
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15389 / SIGLEC5 / sialic acid binding Ig like lectin 5ENSG0000010550177
AC018755.2ENSG0000026850077
Q9NYZ4 / SIGLEC8 / sialic acid binding Ig like lectin 8ENSG0000010536650
Q9Y286 / SIGLEC7 / sialic acid binding Ig like lectin 7ENSG0000016899549
Q96PQ1 / SIGLEC12 / sialic acid binding Ig like lectin 12 (gene/pseudogene)ENSG0000025452148
Q9Y336 / SIGLEC9 / sialic acid binding Ig like lectin 9ENSG0000012945048
Q96LC7 / SIGLEC10 / sialic acid binding Ig like lectin 10ENSG0000014251248
Q96RL6 / SIGLEC11 / sialic acid binding Ig like lectin 11ENSG0000016164048
O43699 / SIGLEC6 / sialic acid binding Ig like lectin 6ENSG0000010549245
CD33 / P20138 / CD33 moleculeENSG0000010538338
MAG / P20916 / myelin associated glycoproteinENSG0000010569524
AC011452.1ENSG000002691791


Protein motifs (from Interpro)
Interpro ID Name
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
DAP12 interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000011600 O43914 / TYROBP / TYRO protein tyrosine kinase binding protein  / reaction / complex






 

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