ENSG00000105383


Homo sapiens

Features
Gene ID: ENSG00000105383
  
Biological name :CD33
  
Synonyms : CD33 / CD33 molecule / P20138
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.41
Gene start: 51225064
Gene end: 51243860
  
Corresponding Affymetrix probe sets: 206120_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410126
Ensembl peptide - ENSP00000262262
Ensembl peptide - ENSP00000375673
Ensembl peptide - ENSP00000403331
NCBI entrez gene - 945     See in Manteia.
OMIM - 159590
RefSeq - XM_017027510
RefSeq - NM_001082618
RefSeq - NM_001177608
RefSeq - NM_001772
RefSeq - XM_011527531
RefSeq - XM_011527532
RefSeq - XM_017027508
RefSeq - XM_017027509
RefSeq Peptide - NP_001076087
RefSeq Peptide - NP_001171079
RefSeq Peptide - NP_001763
swissprot - Q546G0
swissprot - B4DF51
swissprot - P20138
Ensembl - ENSG00000105383
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-24p1.7ENSDARG00000089404Danio rerio
 SiglechENSMUSG00000051504Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O43699 / SIGLEC6 / sialic acid binding Ig like lectin 6ENSG0000010549258
Q9NYZ4 / SIGLEC8 / sialic acid binding Ig like lectin 8ENSG0000010536654
Q9Y286 / SIGLEC7 / sialic acid binding Ig like lectin 7ENSG0000016899552
AC018755.2ENSG0000026850051
Q9Y336 / SIGLEC9 / sialic acid binding Ig like lectin 9ENSG0000012945051
O15389 / SIGLEC5 / sialic acid binding Ig like lectin 5ENSG0000010550151
Q96PQ1 / SIGLEC12 / sialic acid binding Ig like lectin 12 (gene/pseudogene)ENSG0000025452149
Q96LC7 / SIGLEC10 / sialic acid binding Ig like lectin 10ENSG0000014251242
Q08ET2 / SIGLEC14 / sialic acid binding Ig like lectin 14ENSG0000025441541
Q96RL6 / SIGLEC11 / sialic acid binding Ig like lectin 11ENSG0000016164040
MAG / P20916 / myelin associated glycoproteinENSG0000010569524
AC011452.1ENSG000002691790


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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