ENSG00000105371


Homo sapiens

Features
Gene ID: ENSG00000105371
  
Biological name :ICAM4
  
Synonyms : ICAM4 / intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) / Q14773
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.2
Gene start: 10286967
Gene end: 10288522
  
Corresponding Affymetrix probe sets: 207194_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000342114
Ensembl peptide - ENSP00000370147
Ensembl peptide - ENSP00000377320
NCBI entrez gene - 3386     See in Manteia.
OMIM - 614088
RefSeq - NM_001544
RefSeq - NM_001039132
RefSeq - NM_022377
RefSeq Peptide - NP_001034221
RefSeq Peptide - NP_001535
RefSeq Peptide - NP_071772
swissprot - Q14773
swissprot - U5U6P8
Ensembl - ENSG00000105371
  
Related genetic diseases (OMIM): 111250 - [Blood group, Landsteiner-Wiener], 111250
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Icam4ENSMUSG00000001014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ICAM5 / Q9UMF0 / intercellular adhesion molecule 5ENSG0000010537621
ICAM1 / P05362 / intercellular adhesion molecule 1ENSG0000009033918
ICAM2 / P13598 / intercellular adhesion molecule 2ENSG0000010862216
ICAM3 / P32942 / intercellular adhesion molecule 3ENSG0000007666215


Protein motifs (from Interpro)
Interpro ID Name
 IPR003987  Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
 IPR013768  Intercellular adhesion molecule, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0005178 integrin binding TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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