ENSG00000076662


Homo sapiens

Features
Gene ID: ENSG00000076662
  
Biological name :ICAM3
  
Synonyms : ICAM3 / intercellular adhesion molecule 3 / P32942
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 10333776
Gene end: 10339823
  
Corresponding Affymetrix probe sets: 204949_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468230
Ensembl peptide - ENSP00000468282
Ensembl peptide - ENSP00000468333
Ensembl peptide - ENSP00000160262
Ensembl peptide - ENSP00000466081
Ensembl peptide - ENSP00000466501
Ensembl peptide - ENSP00000467232
Ensembl peptide - ENSP00000467770
NCBI entrez gene - 3385     See in Manteia.
OMIM - 146631
RefSeq - NM_001320606
RefSeq - NM_001320608
RefSeq - NM_002162
RefSeq - NM_001320605
RefSeq Peptide - NP_001307534
RefSeq Peptide - NP_001307535
RefSeq Peptide - NP_001307537
RefSeq Peptide - NP_002153
swissprot - P32942
swissprot - A0A024R7C1
swissprot - K7ELH4
swissprot - K7EMH0
swissprot - K7EP52
swissprot - K7EQC7
swissprot - K7ERF0
swissprot - K7ERJ4
swissprot - K7ERN2
Ensembl - ENSG00000076662
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ICAM5 / Q9UMF0 / intercellular adhesion molecule 5ENSG0000010537649
ICAM1 / P05362 / intercellular adhesion molecule 1ENSG0000009033945
ICAM2 / P13598 / intercellular adhesion molecule 2ENSG0000010862214
ICAM4 / Q14773 / intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)ENSG000001053718


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR003987  Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
 IPR003988  Intercellular adhesion molecule
 IPR007110  Immunoglobulin-like domain
 IPR013768  Intercellular adhesion molecule, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Integrin cell surface interactions
CD209 (DC-SIGN) signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000090659 CD209 / Q9NNX6 / CD209 molecule  / complex / reaction






 

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