ENSG00000108622


Homo sapiens

Features
Gene ID: ENSG00000108622
  
Biological name :ICAM2
  
Synonyms : ICAM2 / intercellular adhesion molecule 2 / P13598
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q23.3
Gene start: 64002594
Gene end: 64020634
  
Corresponding Affymetrix probe sets: 204683_at (Human Genome U133 Plus 2.0 Array)   213620_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464665
Ensembl peptide - ENSP00000462617
Ensembl peptide - ENSP00000462579
Ensembl peptide - ENSP00000415283
Ensembl peptide - ENSP00000392634
Ensembl peptide - ENSP00000388666
Ensembl peptide - ENSP00000463199
Ensembl peptide - ENSP00000464331
Ensembl peptide - ENSP00000464372
Ensembl peptide - ENSP00000463862
Ensembl peptide - ENSP00000463945
NCBI entrez gene - 3384     See in Manteia.
OMIM - 146630
RefSeq - NM_001099788
RefSeq - NM_000873
RefSeq - NM_001099786
RefSeq - NM_001099787
RefSeq - NM_001099789
RefSeq Peptide - NP_000864
RefSeq Peptide - NP_001093259
RefSeq Peptide - NP_001093258
RefSeq Peptide - NP_001093257
RefSeq Peptide - NP_001093256
swissprot - Q6FHE2
swissprot - J3KSR9
swissprot - J3QKR4
swissprot - J3QQR8
swissprot - J3QQX6
swissprot - J3QRQ1
swissprot - J3QRT5
swissprot - P13598
Ensembl - ENSG00000108622
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Icam2ENSMUSG00000001029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ICAM5 / Q9UMF0 / intercellular adhesion molecule 5ENSG0000010537629
ICAM1 / P05362 / intercellular adhesion molecule 1ENSG0000009033928
ICAM3 / P32942 / intercellular adhesion molecule 3ENSG0000007666228
ICAM4 / Q14773 / intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)ENSG0000010537116


Protein motifs (from Interpro)
Interpro ID Name
 IPR003987  Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
 IPR003988  Intercellular adhesion molecule
 IPR013768  Intercellular adhesion molecule, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR015653  Intercellular adhesion molecule 2
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0001931 uropod IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005902 microvillus ISS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032154 cleavage furrow IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0005178 integrin binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Integrin cell surface interactions
CD209 (DC-SIGN) signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000090659 CD209 / Q9NNX6 / CD209 molecule  / complex / reaction






 

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