ENSMUSG00000001029


Mus musculus

Features
Gene ID: ENSMUSG00000001029
  
Biological name :Icam2
  
Synonyms : Icam2 / Intercellular adhesion molecule 2 / P35330
  
Possible biological names infered from orthology : P13598
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 106377656
Gene end: 106388075
  
Corresponding Affymetrix probe sets: 10392177 (MoGene1.0st)   1448862_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133315
Ensembl peptide - ENSMUSP00000001055
Ensembl peptide - ENSMUSP00000102426
Ensembl peptide - ENSMUSP00000118043
NCBI entrez gene - 15896     See in Manteia.
MGI - MGI:96394
RefSeq - XM_006532303
RefSeq - XM_011248761
RefSeq - XM_011248762
RefSeq - XM_011248763
RefSeq - NM_010494
RefSeq Peptide - NP_034624
swissprot - P35330
swissprot - G5E8M9
swissprot - B1ARJ2
swissprot - G3UWJ5
Ensembl - ENSMUSG00000001029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ICAM2ENSG00000108622Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tcam1 / testicular cell adhesion molecule 1ENSMUSG0000002071236
Icam1 / P13597 / intercellular adhesion molecule 1 / P05362*ENSMUSG0000003740529
Icam5 / Q60625 / Intercellular adhesion molecule 5 / Q9UMF0*ENSMUSG0000003217427
Icam4 / Q9ERM2 / Intercellular adhesion molecule 4 / Q14773* / intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)*ENSMUSG0000000101422


Protein motifs (from Interpro)
Interpro ID Name
 IPR003987  Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
 IPR003988  Intercellular adhesion molecule
 IPR013768  Intercellular adhesion molecule, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR015653  Intercellular adhesion molecule 2
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0001931 uropod IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Integrin cell surface interactions
CD209 (DC-SIGN) signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001952 increased airway responsiveness "more easily provoked into bronchoconstriction in bronchial provocation tests" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: KitlSl-20J/KitlSl-20J
Genetic Background: C57BL/6J-KitlSl-20J/J

 MP:0002413 abnormal megakaryoblast morphology/development "anomalous structure or development of the progenitor cells of the thrombocytic (platelet) line of cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: KitlSl-20J/KitlSl-20J
Genetic Background: C57BL/6J-KitlSl-20J/J

 MP:0002465 abnormal eosinophil physiology "abnormal function of the leukocyte that stains with eosin and is involved in clearance of parasitic infections and in allergic reactions " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: KitlSl-20J/KitlSl-20J
Genetic Background: C57BL/6J-KitlSl-20J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030830 Itgal / P24063 / Integrin alpha-L / P20701* / integrin subunit alpha L*  / reaction / complex






 

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