ENSG00000090659


Homo sapiens

Features
Gene ID: ENSG00000090659
  
Biological name :CD209
  
Synonyms : CD209 / CD209 molecule / Q9NNX6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 7739994
Gene end: 7747564
  
Corresponding Affymetrix probe sets: 1555729_a_at (Human Genome U133 Plus 2.0 Array)   207277_at (Human Genome U133 Plus 2.0 Array)   207278_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000471348
Ensembl peptide - ENSP00000470658
Ensembl peptide - ENSP00000471137
Ensembl peptide - ENSP00000204801
Ensembl peptide - ENSP00000315407
Ensembl peptide - ENSP00000315477
Ensembl peptide - ENSP00000346373
Ensembl peptide - ENSP00000377716
Ensembl peptide - ENSP00000377728
Ensembl peptide - ENSP00000468827
Ensembl peptide - ENSP00000470530
NCBI entrez gene - 30835     See in Manteia.
OMIM - 604672
RefSeq - XM_005272472
RefSeq - NM_001144893
RefSeq - NM_001144894
RefSeq - NM_001144895
RefSeq - NM_001144896
RefSeq - NM_001144897
RefSeq - NM_001144899
RefSeq - NM_021155
RefSeq Peptide - NP_001138371
RefSeq Peptide - NP_066978
RefSeq Peptide - NP_001138366
RefSeq Peptide - NP_001138367
RefSeq Peptide - NP_001138365
RefSeq Peptide - NP_001138368
RefSeq Peptide - NP_001138369
swissprot - X6RB12
swissprot - M0R0P0
swissprot - Q9NNX6
swissprot - M0QZG5
Ensembl - ENSG00000090659
  
Related genetic diseases (OMIM): 607948 - {Mycobacterium tuberculosis, susceptibility to}, 607948
  609423 - {HIV type 1, susceptibility to}, 609423
  614371 - {Dengue fever, protection against}, 614371
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:174904ENSDARG00000059049Danio rerio
 Cd209aENSMUSG00000031494Mus musculus
 Cd209bENSMUSG00000065987Mus musculus
 Cd209cENSMUSG00000040165Mus musculus
 Cd209dENSMUSG00000031495Mus musculus
 Cd209eENSMUSG00000040197Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLEC4M / Q9H2X3 / C-type lectin domain family 4 member MENSG0000010493866
Q8IUN9 / CLEC10A / C-type lectin domain containing 10AENSG0000013251419
CLEC4E / Q9ULY5 / C-type lectin domain family 4 member EENSG0000016652317
ASGR2 / P07307 / asialoglycoprotein receptor 2ENSG0000016194417
Q6ZS10 / CLEC17A / C-type lectin domain containing 17AENSG0000018791217
ASGR1 / P07306 / asialoglycoprotein receptor 1ENSG0000014150517
CLEC4G / Q6UXB4 / C-type lectin domain family 4 member GENSG0000018256616
FCER2 / P06734 / Fc fragment of IgE receptor IIENSG0000010492115
CD207 / Q9UJ71 / CD207 moleculeENSG0000011603113
CLEC4F / Q8N1N0 / C-type lectin domain family 4 member FENSG0000015267212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR023129  MTH889-like domain superfamily
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules TAS
 biological_processGO:0007159 leukocyte cell-cell adhesion NAS
 biological_processGO:0009988 cell-cell recognition TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019048 modulation by virus of host morphology or physiology TAS
 biological_processGO:0019062 virion attachment to host cell TAS
 biological_processGO:0019079 viral genome replication NAS
 biological_processGO:0019882 antigen processing and presentation NAS
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0042102 positive regulation of T cell proliferation IDA
 biological_processGO:0042129 regulation of T cell proliferation IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0046968 peptide antigen transport NAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:0097323 B cell adhesion IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface HDA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005537 mannose binding TAS
 molecular_functionGO:0030246 carbohydrate binding NAS
 molecular_functionGO:0042605 peptide antigen binding NAS
 molecular_functionGO:0046790 virion binding TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
CD209 (DC-SIGN) signaling
Butyrophilin (BTN) family interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000076662 ICAM3 / P32942 / intercellular adhesion molecule 3  / complex / reaction
 ENSG00000112763 BTN2A1 / Q7KYR7 / butyrophilin subfamily 2 member A1  / complex / reaction
 ENSG00000108622 ICAM2 / P13598 / intercellular adhesion molecule 2  / complex / reaction






 

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