ENSG00000141505


Homo sapiens

Features
Gene ID: ENSG00000141505
  
Biological name :ASGR1
  
Synonyms : ASGR1 / asialoglycoprotein receptor 1 / P07306
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7173431
Gene end: 7179564
  
Corresponding Affymetrix probe sets: 206743_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481182
Ensembl peptide - ENSP00000459896
Ensembl peptide - ENSP00000467511
Ensembl peptide - ENSP00000269299
Ensembl peptide - ENSP00000370307
Ensembl peptide - ENSP00000458530
Ensembl peptide - ENSP00000458803
Ensembl peptide - ENSP00000459169
NCBI entrez gene - 432     See in Manteia.
OMIM - 108360
RefSeq - XM_011523861
RefSeq - NM_001197216
RefSeq - NM_001671
RefSeq Peptide - NP_001662
RefSeq Peptide - NP_001184145
swissprot - Q6FGQ5
swissprot - I3L129
swissprot - P07306
swissprot - I3L1F8
swissprot - J3QSZ2
swissprot - I3L2S9
swissprot - K7EPS5
Ensembl - ENSG00000141505
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-283g2.2ENSDARG00000108953Danio rerio
 si:ch211-283g2.3ENSDARG00000046092Danio rerio
 si:ch73-361h17.1ENSDARG00000095963Danio rerio
 Asgr1ENSMUSG00000020884Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASGR2 / P07307 / asialoglycoprotein receptor 2ENSG0000016194458
Q8IUN9 / CLEC10A / C-type lectin domain containing 10AENSG0000013251458
Q6ZS10 / CLEC17A / C-type lectin domain containing 17AENSG0000018791226
FCER2 / P06734 / Fc fragment of IgE receptor IIENSG0000010492123
CD209 / Q9NNX6 / CD209 moleculeENSG0000009065923
CLEC4M / Q9H2X3 / C-type lectin domain family 4 member MENSG0000010493823
CLEC4G / Q6UXB4 / C-type lectin domain family 4 member GENSG0000018256622
CLEC4E / Q9ULY5 / C-type lectin domain family 4 member EENSG0000016652319
CLEC4F / Q8N1N0 / C-type lectin domain family 4 member FENSG0000015267219
CD207 / Q9UJ71 / CD207 moleculeENSG0000011603119


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0018279 protein N-linked glycosylation via asparagine TAS
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004873 asialoglycoprotein receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Asparagine N-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000161944 ASGR2 / P07307 / asialoglycoprotein receptor 2  / complex






 

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