ENSG00000104921


Homo sapiens

Features
Gene ID: ENSG00000104921
  
Biological name :FCER2
  
Synonyms : FCER2 / Fc fragment of IgE receptor II / P06734
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 7688758
Gene end: 7702146
  
Corresponding Affymetrix probe sets: 206759_at (Human Genome U133 Plus 2.0 Array)   206760_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264072
Ensembl peptide - ENSP00000353178
Ensembl peptide - ENSP00000471974
Ensembl peptide - ENSP00000472067
NCBI entrez gene - 2208     See in Manteia.
OMIM - 151445
RefSeq - XM_005272462
RefSeq - NM_001207019
RefSeq - NM_001220500
RefSeq - NM_002002
RefSeq Peptide - NP_001193948
RefSeq Peptide - NP_001207429
RefSeq Peptide - NP_001993
swissprot - K3W4U1
swissprot - M0R1R5
swissprot - P06734
Ensembl - ENSG00000104921
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:174904ENSDARG00000059049Danio rerio
 Fcer2aENSMUSG00000005540Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLEC4G / Q6UXB4 / C-type lectin domain family 4 member GENSG0000018256625
ASGR2 / P07307 / asialoglycoprotein receptor 2ENSG0000016194422
Q8IUN9 / CLEC10A / C-type lectin domain containing 10AENSG0000013251422
Q6ZS10 / CLEC17A / C-type lectin domain containing 17AENSG0000018791222
ASGR1 / P07306 / asialoglycoprotein receptor 1ENSG0000014150521
CD209 / Q9NNX6 / CD209 moleculeENSG0000009065919
CLEC4M / Q9H2X3 / C-type lectin domain family 4 member MENSG0000010493819
CD207 / Q9UJ71 / CD207 moleculeENSG0000011603119
CLEC4E / Q9ULY5 / C-type lectin domain family 4 member EENSG0000016652317
CLEC4F / Q8N1N0 / C-type lectin domain family 4 member FENSG0000015267215


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin IEA
 biological_processGO:0007219 Notch signaling pathway TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IDA
 biological_processGO:0051712 positive regulation of killing of cells of other organism IDA
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005178 integrin binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019863 IgE binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NOTCH2 intracellular domain regulates transcription
Interleukin-10 signaling
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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