ENSG00000161944


Homo sapiens

Features
Gene ID: ENSG00000161944
  
Biological name :ASGR2
  
Synonyms : ASGR2 / asialoglycoprotein receptor 2 / P07307
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7101322
Gene end: 7115700
  
Corresponding Affymetrix probe sets: 206130_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000254850
Ensembl peptide - ENSP00000347140
Ensembl peptide - ENSP00000405844
Ensembl peptide - ENSP00000458835
NCBI entrez gene - 433     See in Manteia.
OMIM - 108361
RefSeq - XM_017024653
RefSeq - NM_001181
RefSeq - NM_001201352
RefSeq - NM_080912
RefSeq - NM_080913
RefSeq - NM_080914
RefSeq - XM_011523862
RefSeq - XM_011523863
RefSeq - XM_011523864
RefSeq - XM_011523865
RefSeq - XM_011523866
RefSeq - XM_017024651
RefSeq - XM_017024652
RefSeq - XM_005256648
RefSeq - XM_006721524
RefSeq - XM_006721526
RefSeq Peptide - NP_001172
RefSeq Peptide - NP_001188281
RefSeq Peptide - NP_550434
RefSeq Peptide - NP_550435
RefSeq Peptide - NP_550436
swissprot - P07307
swissprot - I3L1H2
Ensembl - ENSG00000161944
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-283g2.2ENSDARG00000108953Danio rerio
 si:ch211-283g2.3ENSDARG00000046092Danio rerio
 si:ch73-361h17.1ENSDARG00000095963Danio rerio
 Asgr2ENSMUSG00000040963Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASGR1 / P07306 / asialoglycoprotein receptor 1ENSG0000014150555
Q8IUN9 / CLEC10A / C-type lectin domain containing 10AENSG0000013251446
CLEC4G / Q6UXB4 / C-type lectin domain family 4 member GENSG0000018256624
CD209 / Q9NNX6 / CD209 moleculeENSG0000009065923
CLEC4M / Q9H2X3 / C-type lectin domain family 4 member MENSG0000010493823
FCER2 / P06734 / Fc fragment of IgE receptor IIENSG0000010492123
Q6ZS10 / CLEC17A / C-type lectin domain containing 17AENSG0000018791222
CLEC4F / Q8N1N0 / C-type lectin domain family 4 member FENSG0000015267220
CLEC4E / Q9ULY5 / C-type lectin domain family 4 member EENSG0000016652320
CD207 / Q9UJ71 / CD207 moleculeENSG0000011603118


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0009100 glycoprotein metabolic process IEA
 biological_processGO:0018279 protein N-linked glycosylation via asparagine TAS
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0055088 lipid homeostasis IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004873 asialoglycoprotein receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Asparagine N-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141505 ASGR1 / P07306 / asialoglycoprotein receptor 1  / complex






 

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