ENSG00000166523


Homo sapiens

Features
Gene ID: ENSG00000166523
  
Biological name :CLEC4E
  
Synonyms : CLEC4E / C-type lectin domain family 4 member E / Q9ULY5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.31
Gene start: 8533305
Gene end: 8540963
  
Corresponding Affymetrix probe sets: 219859_at (Human Genome U133 Plus 2.0 Array)   222934_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387737
Ensembl peptide - ENSP00000443034
Ensembl peptide - ENSP00000443328
Ensembl peptide - ENSP00000299663
Ensembl peptide - ENSP00000404994
NCBI entrez gene - 26253     See in Manteia.
OMIM - 609962
RefSeq - XM_011520615
RefSeq - NM_014358
RefSeq - XM_011520614
RefSeq Peptide - NP_055173
swissprot - F5H5X7
swissprot - Q9ULY5
swissprot - F8WFA1
swissprot - H0YGH9
Ensembl - ENSG00000166523
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01058107.1ENSDARG00000112826Danio rerio
 cd209ENSDARG00000029461Danio rerio
 CR847844.1ENSDARG00000087245Danio rerio
 CR847844.2ENSDARG00000102680Danio rerio
 si:ch211-170d8.8ENSDARG00000090945Danio rerio
 si:ch211-214k5.3ENSDARG00000043894Danio rerio
 si:ch73-111e15.1ENSDARG00000008182Danio rerio
 si:ch73-122g19.1ENSDARG00000069323Danio rerio
 si:dkey-181c13.1ENSDARG00000025150Danio rerio
 si:dkey-187i8.2ENSDARG00000096624Danio rerio
 zmp:0000000924ENSDARG00000088219Danio rerio
 zmp:0000000937ENSDARG00000088727Danio rerio
 Clec4eENSMUSG00000030142Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD209 / Q9NNX6 / CD209 moleculeENSG0000009065932
CLEC4M / Q9H2X3 / C-type lectin domain family 4 member MENSG0000010493830
ASGR2 / P07307 / asialoglycoprotein receptor 2ENSG0000016194429
Q6ZS10 / CLEC17A / C-type lectin domain containing 17AENSG0000018791228
Q8IUN9 / CLEC10A / C-type lectin domain containing 10AENSG0000013251428
ASGR1 / P07306 / asialoglycoprotein receptor 1ENSG0000014150525
CD207 / Q9UJ71 / CD207 moleculeENSG0000011603124
FCER2 / P06734 / Fc fragment of IgE receptor IIENSG0000010492124
CLEC4G / Q6UXB4 / C-type lectin domain family 4 member GENSG0000018256624
CLEC4F / Q8N1N0 / C-type lectin domain family 4 member FENSG0000015267219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002292 T cell differentiation involved in immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0038094 Fc-gamma receptor signaling pathway IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0030246 carbohydrate binding TAS


Pathways (from Reactome)
Pathway description
Dectin-2 family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000010810 FYN / P06241 / FYN proto-oncogene, Src family tyrosine kinase  / reaction
 ENSG00000165025 SYK / P43405 / spleen associated tyrosine kinase  / reaction / complex
 ENSG00000197943 PLCG2 / P16885 / phospholipase C gamma 2  / reaction / complex
 ENSG00000158869 FCER1G / P30273 / Fc fragment of IgE receptor Ig  / complex
 ENSG00000254087 LYN / P07948 / LYN proto-oncogene, Src family tyrosine kinase  / reaction






 

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