ENSG00000105576


Homo sapiens

Features
Gene ID: ENSG00000105576
  
Biological name :TNPO2
  
Synonyms : O14787 / TNPO2 / transportin 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.13
Gene start: 12699194
Gene end: 12724011
  
Corresponding Affymetrix probe sets: 210585_s_at (Human Genome U133 Plus 2.0 Array)   215844_at (Human Genome U133 Plus 2.0 Array)   221506_s_at (Human Genome U133 Plus 2.0 Array)   221507_at (Human Genome U133 Plus 2.0 Array)   226428_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468434
Ensembl peptide - ENSP00000468739
Ensembl peptide - ENSP00000468698
Ensembl peptide - ENSP00000468642
Ensembl peptide - ENSP00000349321
Ensembl peptide - ENSP00000397379
Ensembl peptide - ENSP00000407182
Ensembl peptide - ENSP00000465625
Ensembl peptide - ENSP00000466011
Ensembl peptide - ENSP00000466421
Ensembl peptide - ENSP00000466446
Ensembl peptide - ENSP00000467115
Ensembl peptide - ENSP00000468101
NCBI entrez gene - 30000     See in Manteia.
OMIM - 603002
RefSeq - NM_001136196
RefSeq - NM_013433
RefSeq - NM_001136195
RefSeq Peptide - NP_001129667
RefSeq Peptide - NP_001129668
RefSeq Peptide - NP_038461
swissprot - K7ESJ3
swissprot - A0A075B780
swissprot - O14787
swissprot - A0A024R7F7
swissprot - K7ELC3
swissprot - K7EMA3
swissprot - K7ENW1
swissprot - K7ESC1
swissprot - K7ESG1
Ensembl - ENSG00000105576
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO017722.1ENSDARG00000113296Danio rerio
 LO017798.1ENSDARG00000042887Danio rerio
 tnpo2ENSDARG00000038239Danio rerio
 Tnpo2ENSMUSG00000031691Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNPO1 / Q92973 / transportin 1ENSG0000008331285


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IBA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0006610 ribosomal protein import into nucleus IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0031965 nuclear membrane IBA
 cellular_componentGO:0034399 nuclear periphery IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding TAS
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0008565 protein transporter activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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