ENSG00000105642


Homo sapiens

Features
Gene ID: ENSG00000105642
  
Biological name :KCNN1
  
Synonyms : KCNN1 / potassium calcium-activated channel subfamily N member 1 / Q92952
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 17951293
Gene end: 18000080
  
Corresponding Affymetrix probe sets: 206231_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484926
Ensembl peptide - ENSP00000476519
Ensembl peptide - ENSP00000477114
NCBI entrez gene - 3780     See in Manteia.
OMIM - 602982
RefSeq - XM_011528005
RefSeq - NM_002248
RefSeq - XM_005259905
RefSeq - XM_005259906
RefSeq - XM_005259907
RefSeq - XM_011528004
RefSeq Peptide - NP_002239
swissprot - Q92952
swissprot - V9GYV2
swissprot - A0A087X2E7
Ensembl - ENSG00000105642
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnn1aENSDARG00000091306Danio rerio
 kcnn1bENSDARG00000023546Danio rerio
 KCNN1ENSGALG00000031411Gallus gallus
 Kcnn1ENSMUSG00000002908Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNN2 / Q9H2S1 / potassium calcium-activated channel subfamily N member 2ENSG0000008070970
KCNN3 / Q9UGI6 / potassium calcium-activated channel subfamily N member 3ENSG0000014360367
KCNN4 / O15554 / potassium calcium-activated channel subfamily N member 4ENSG0000010478334


Protein motifs (from Interpro)
Interpro ID Name
 IPR004178  Calmodulin-binding domain
 IPR013099  Potassium channel domain
 IPR015449  Potassium channel, calcium-activated, SK
 IPR036122  SK, calmodulin-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0016286 small conductance calcium-activated potassium channel activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105642 KCNN1 / Q92952 / potassium calcium-activated channel subfamily N member 1  / complex
 ENSG00000080709 KCNN2 / Q9H2S1 / potassium calcium-activated channel subfamily N member 2  / complex
 ENSG00000143603 KCNN3 / Q9UGI6 / potassium calcium-activated channel subfamily N member 3  / complex






 

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