ENSG00000143603


Homo sapiens

Features
Gene ID: ENSG00000143603
  
Biological name :KCNN3
  
Synonyms : KCNN3 / potassium calcium-activated channel subfamily N member 3 / Q9UGI6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 154697455
Gene end: 154870280
  
Corresponding Affymetrix probe sets: 205902_at (Human Genome U133 Plus 2.0 Array)   205903_s_at (Human Genome U133 Plus 2.0 Array)   231103_at (Human Genome U133 Plus 2.0 Array)   244040_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000271915
Ensembl peptide - ENSP00000481848
Ensembl peptide - ENSP00000354764
Ensembl peptide - ENSP00000351295
NCBI entrez gene - 3782     See in Manteia.
OMIM - 602983
RefSeq - NM_001204087
RefSeq - NM_002249
RefSeq - NM_170782
RefSeq Peptide - NP_001191016
RefSeq Peptide - NP_740752
RefSeq Peptide - NP_002240
swissprot - Q9UGI6
swissprot - A0A087WYJ0
swissprot - A0A0A0MQW9
Ensembl - ENSG00000143603
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNN3ENSGALG00000030554Gallus gallus
 Kcnn3ENSMUSG00000000794Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNN2 / Q9H2S1 / potassium calcium-activated channel subfamily N member 2ENSG0000008070957
KCNN1 / Q92952 / potassium calcium-activated channel subfamily N member 1ENSG0000010564249
KCNN4 / O15554 / potassium calcium-activated channel subfamily N member 4ENSG0000010478325


Protein motifs (from Interpro)
Interpro ID Name
 IPR004178  Calmodulin-binding domain
 IPR013099  Potassium channel domain
 IPR015449  Potassium channel, calcium-activated, SK
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR036122  SK, calmodulin-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043025 neuronal cell body IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0016286 small conductance calcium-activated potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000080709 KCNN2 / Q9H2S1 / potassium calcium-activated channel subfamily N member 2  / complex
 ENSG00000143603 KCNN3 / Q9UGI6 / potassium calcium-activated channel subfamily N member 3  / complex
 ENSG00000105642 KCNN1 / Q92952 / potassium calcium-activated channel subfamily N member 1  / complex






 

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