ENSG00000105679


Homo sapiens

Features
Gene ID: ENSG00000105679
  
Biological name :GAPDHS
  
Synonyms : GAPDHS / glyceraldehyde-3-phosphate dehydrogenase, spermatogenic / O14556
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35533412
Gene end: 35545316
  
Corresponding Affymetrix probe sets: 207116_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467255
Ensembl peptide - ENSP00000222286
Ensembl peptide - ENSP00000466432
NCBI entrez gene - 26330     See in Manteia.
OMIM - 609169
RefSeq - XM_017026579
RefSeq - NM_014364
RefSeq Peptide - NP_055179
swissprot - K7EP73
swissprot - A0A0K0K1K1
swissprot - O14556
swissprot - K7EMB2
Ensembl - ENSG00000105679
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gapdhsENSDARG00000039914Danio rerio
 GapdhsENSMUSG00000061099Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GAPDH / P04406 / glyceraldehyde-3-phosphate dehydrogenaseENSG0000011164056


Protein motifs (from Interpro)
Interpro ID Name
 IPR006424  Glyceraldehyde-3-phosphate dehydrogenase, type I
 IPR020828  Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
 IPR020829  Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
 IPR020830  Glyceraldehyde 3-phosphate dehydrogenase, active site
 IPR020831  Glyceraldehyde/Erythrose phosphate dehydrogenase family
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006094 gluconeogenesis TAS
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0030317 flagellated sperm motility ISS
 biological_processGO:0045821 positive regulation of glycolytic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061621 canonical glycolysis TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity EXP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0050661 NADP binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Glycolysis
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105679 GAPDHS / O14556 / glyceraldehyde-3-phosphate dehydrogenase, spermatogenic  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr