ENSG00000106346


Homo sapiens

Features
Gene ID: ENSG00000106346
  
Biological name :USP42
  
Synonyms : Q9H9J4 / ubiquitin specific peptidase 42 / USP42
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.1
Gene start: 6104884
Gene end: 6161564
  
Corresponding Affymetrix probe sets: 226172_at (Human Genome U133 Plus 2.0 Array)   226174_at (Human Genome U133 Plus 2.0 Array)   226176_s_at (Human Genome U133 Plus 2.0 Array)   226669_at (Human Genome U133 Plus 2.0 Array)   228982_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430568
Ensembl peptide - ENSP00000385964
Ensembl peptide - ENSP00000431127
Ensembl peptide - ENSP00000408217
Ensembl peptide - ENSP00000416910
Ensembl peptide - ENSP00000301962
NCBI entrez gene - 84132     See in Manteia.
RefSeq - XM_011515578
RefSeq - NM_032172
RefSeq - XM_005249883
RefSeq - XM_006715790
RefSeq - XM_006715791
RefSeq - XM_011515573
RefSeq - XM_011515574
RefSeq - XM_011515577
RefSeq Peptide - NP_115548
swissprot - E5RJP3
swissprot - C9JPC9
swissprot - E7EWZ4
swissprot - B4DP25
swissprot - Q9H9J4
swissprot - F8WD92
Ensembl - ENSG00000106346
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp42ENSDARG00000077300Danio rerio
 USP42ENSGALG00000003378Gallus gallus
 Usp42ENSMUSG00000051306Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP36 / Q9P275 / ubiquitin specific peptidase 36ENSG0000005548328
C9J2P7 / USP17L15 / ubiquitin specific peptidase 17-like family member 15ENSG0000022356919
A6NCW7 / USP17L4 / ubiquitin specific peptidase 17-like family member 4ENSG0000023612518
D6RBQ6 / USP17L17 / ubiquitin specific peptidase 17-like family member 17ENSG0000024910418
C9JPN9 / USP17L12 / ubiquitin specific peptidase 17-like family member 12ENSG0000022755118
Q0WX57 / USP17L27 / ubiquitin specific peptidase 17-like family member 27ENSG0000023578018
D6RA61 / USP17L22 / ubiquitin specific peptidase 17-like family member 22ENSG0000024893318
D6RCP7 / USP17L19 / ubiquitin specific peptidase 17-like family member 19ENSG0000024892018
Q0WX57 / USP17L29 / ubiquitin specific peptidase 17-like family member 29ENSG0000023163718
Q0WX57 / USP17L26 / ubiquitin specific peptidase 17-like family member 26ENSG0000022957918
Q0WX57 / USP17L25 / ubiquitin specific peptidase 17-like family member 25ENSG0000023043018
Q0WX57 / USP17L28 / ubiquitin specific peptidase 17-like family member 28ENSG0000023105118
P0C7I0 / USP17L8 / ubiquitin specific peptidase 17-like family member 8ENSG0000023703818
D6R9N7 / USP17L18 / ubiquitin specific peptidase 17-like family member 18ENSG0000025084418
D6R901 / USP17L21 / ubiquitin specific peptidase 17-like family member 21ENSG0000024981118
Q0WX57 / USP17L30 / ubiquitin specific peptidase 17-like family member 30ENSG0000022885618
C9JJH3 / USP17L10 / ubiquitin specific peptidase 17-like family member 10ENSG0000023139618
C9JLJ4 / USP17L13 / ubiquitin specific peptidase 17-like family member 13ENSG0000023239918
A8MUK1 / USP17L5 / ubiquitin specific peptidase 17-like family member 5ENSG0000022714018
D6RJB6 / USP17L20 / ubiquitin specific peptidase 17-like family member 20ENSG0000025074518


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex






 

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