ENSG00000106809


Homo sapiens

Features
Gene ID: ENSG00000106809
  
Biological name :OGN
  
Synonyms : OGN / osteoglycin / P20774
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q22.31
Gene start: 92383967
Gene end: 92404696
  
Corresponding Affymetrix probe sets: 218730_s_at (Human Genome U133 Plus 2.0 Array)   222722_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396709
Ensembl peptide - ENSP00000262551
Ensembl peptide - ENSP00000364711
NCBI entrez gene - 4969     See in Manteia.
OMIM - 602383
RefSeq - NM_024416
RefSeq - NM_014057
RefSeq - NM_033014
RefSeq Peptide - NP_054776
RefSeq Peptide - NP_077727
RefSeq Peptide - NP_148935
swissprot - Q5TBF5
swissprot - P20774
swissprot - A8K0R3
Ensembl - ENSG00000106809
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ognENSDARG00000044132Danio rerio
 zgc:193598ENSDARG00000031489Danio rerio
 OGNENSGALG00000026736Gallus gallus
 OgnENSMUSG00000021390Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPYC / Q99645 / epiphycanENSG0000008378240
OPTC / Q9UBM4 / opticinENSG0000018877039


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027211  Mimecan
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007409 axonogenesis IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 biological_processGO:0042340 keratan sulfate catabolic process TAS
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation ISS
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Keratan sulfate degradation
Defective CHST6 causes MCDC1
Defective ST3GAL3 causes MCT12 and EIEE15
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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