ENSMUSG00000021390


Mus musculus

Features
Gene ID: ENSMUSG00000021390
  
Biological name :Ogn
  
Synonyms : Ogn / osteoglycin / Q62000
  
Possible biological names infered from orthology : P20774
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 49608046
Gene end: 49624501
  
Corresponding Affymetrix probe sets: 10405063 (MoGene1.0st)   1419662_at (Mouse Genome 430 2.0 Array)   1419663_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021822
NCBI entrez gene - 18295     See in Manteia.
MGI - MGI:109278
RefSeq - NM_008760
RefSeq Peptide - NP_032786
swissprot - Q543C5
swissprot - Q62000
Ensembl - ENSMUSG00000021390
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ognENSDARG00000044132Danio rerio
 zgc:193598ENSDARG00000031489Danio rerio
 OGNENSGALG00000026736Gallus gallus
 OGNENSG00000106809Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Epyc / P70186 / Epiphycan / Q99645*ENSMUSG0000001993637
Optc / opticin isoform 4 / Q9UBM4* / opticin*ENSMUSG0000001031137


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027211  Mimecan
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007409 axonogenesis IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Keratan sulfate degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ncoa3tm1b(EUCOMM)Wtsi/Ncoa3+
Genetic Background: C57BL/6N-Ncoa3tm1b(EUCOMM)Wtsi/H

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Myl7tm1(cre)Krc/Myl7+,Prkg1tm2Naw/Prkg1tm2Naw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0003966 abnormal adrenocorticotropin level 
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Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ncoa3tm1b(EUCOMM)Wtsi/Ncoa3+
Genetic Background: C57BL/6N-Ncoa3tm1b(EUCOMM)Wtsi/H

 MP:0005275 abnormal skin tensile strength "change from the normal maximum tension the skin can withstand without tearing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84062]
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Allelic Composition: Myl7tm1(cre)Krc/Myl7+,Prkg1tm2Naw/Prkg1tm2Naw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0008438 abnormal cutaneous collagen fibril morphology "any structural anomaly of the connective tissue bundles in the extracellular matrix of skin tissue that are composed of collagen, and play a role in skin strength and elasticity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Myl7tm1(cre)Krc/Myl7+,Prkg1tm2Naw/Prkg1tm2Naw
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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