ENSMUSG00000010311


Mus musculus

Features
Gene ID: ENSMUSG00000010311
  
Biological name :Optc
  
Synonyms : Optc / opticin isoform 4
  
Possible biological names infered from orthology : opticin / Q9UBM4
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E4
Gene start: 133897199
Gene end: 133907999
  
Corresponding Affymetrix probe sets: 10357858 (MoGene1.0st)   1420578_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115661
Ensembl peptide - ENSMUSP00000117086
Ensembl peptide - ENSMUSP00000120568
Ensembl peptide - ENSMUSP00000123262
NCBI entrez gene - 269120     See in Manteia.
MGI - MGI:2151113
RefSeq - XM_011248028
RefSeq - NM_001160420
RefSeq - NM_001160421
RefSeq - NM_001160422
RefSeq - NM_054076
RefSeq - XM_006529660
RefSeq - XM_006529661
RefSeq - XM_011248027
RefSeq Peptide - NP_001153894
RefSeq Peptide - NP_001153893
RefSeq Peptide - NP_473417
RefSeq Peptide - NP_001153892
swissprot - F6Z4X6
swissprot - E9PUR1
swissprot - G3UVW2
Ensembl - ENSMUSG00000010311
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 optcENSDARG00000014358Danio rerio
 OPTCENSGALG00000003554Gallus gallus
 OPTCENSG00000188770Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Epyc / P70186 / Epiphycan / Q99645*ENSMUSG0000001993635
Ogn / Q62000 / osteoglycin / P20774*ENSMUSG0000002139029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009660 abnormal induced retinal neovascularization "any anomaly in the response to conditions which induce the pathological growth of vessels into the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Thbdtm1.1(THBD)Sltz/Thbdtm1.1(THBD)Sltz
Genetic Background: B6.129(FVB)-Thbdtm1.1(THBD)Sltz Apoetm1Unc

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000050578 Mmp13 / P33435 / Collagenase 3 / P45452* / matrix metallopeptidase 13*  / reaction
 ENSMUSG00000018623 Mmp7 / matrix metallopeptidase 7 / P09237*  / reaction
 ENSMUSG00000031740 Mmp2 / P33434 / 72 kDa type IV collagenase PEX / P08253* / matrix metallopeptidase 2*  / reaction






 

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contact: otassy@igbmc.fr