ENSG00000188770


Homo sapiens

Features
Gene ID: ENSG00000188770
  
Biological name :OPTC
  
Synonyms : OPTC / opticin / Q9UBM4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 203494143
Gene end: 203508864
  
Corresponding Affymetrix probe sets: 223884_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356191
Ensembl peptide - ENSP00000399491
NCBI entrez gene - 26254     See in Manteia.
OMIM - 605127
RefSeq - XM_011509406
RefSeq - NM_014359
RefSeq Peptide - NP_055174
swissprot - Q5T2G3
swissprot - Q9UBM4
Ensembl - ENSG00000188770
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 optcENSDARG00000014358Danio rerio
 OPTCENSGALG00000003554Gallus gallus
 OptcENSMUSG00000010311Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPYC / Q99645 / epiphycanENSG0000008378241
OGN / P20774 / osteoglycinENSG0000010680935


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022617 extracellular matrix disassembly TAS
 cellular_componentGO:0005576 extracellular region TAS
 molecular_functionGO:0005201 extracellular matrix structural constituent TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000087245 MMP2 / P08253 / matrix metallopeptidase 2  / reaction
 ENSG00000137745 MMP13 / P45452 / matrix metallopeptidase 13  / reaction
 ENSG00000137673 MMP7 / P09237 / matrix metallopeptidase 7  / reaction






 

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© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr