ENSG00000107341


Homo sapiens

Features
Gene ID: ENSG00000107341
  
Biological name :UBE2R2
  
Synonyms : Q712K3 / UBE2R2 / ubiquitin conjugating enzyme E2 R2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p13.3
Gene start: 33817567
Gene end: 33920404
  
Corresponding Affymetrix probe sets: 223014_at (Human Genome U133 Plus 2.0 Array)   226954_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263228
NCBI entrez gene - 54926     See in Manteia.
OMIM - 612506
RefSeq - XM_011517949
RefSeq - NM_017811
RefSeq - XM_005251496
RefSeq Peptide - NP_060281
swissprot - Q712K3
Ensembl - ENSG00000107341
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2r2ENSDARG00000058740Danio rerio
 ENSGALG00000035118Gallus gallus
 UBE2R2ENSGALG00000001668Gallus gallus
 Q6ZWZ2ENSMUSG00000036241Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDC34 / P49427 / cell division cycle 34ENSG0000009980479
P62253 / UBE2G1 / ubiquitin conjugating enzyme E2 G1ENSG0000013238836
P60604 / UBE2G2 / ubiquitin conjugating enzyme E2 G2ENSG0000018478732


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006513 protein monoubiquitination IDA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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