ENSG00000184787


Homo sapiens

Features
Gene ID: ENSG00000184787
  
Biological name :UBE2G2
  
Synonyms : P60604 / UBE2G2 / ubiquitin conjugating enzyme E2 G2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.3
Gene start: 44768580
Gene end: 44802019
  
Corresponding Affymetrix probe sets: 1557053_s_at (Human Genome U133 Plus 2.0 Array)   209041_s_at (Human Genome U133 Plus 2.0 Array)   209042_s_at (Human Genome U133 Plus 2.0 Array)   232755_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000331384
Ensembl peptide - ENSP00000338348
Ensembl peptide - ENSP00000418423
Ensembl peptide - ENSP00000420671
NCBI entrez gene - 7327     See in Manteia.
OMIM - 603124
RefSeq - XM_017028469
RefSeq - NM_001202489
RefSeq - NM_003343
RefSeq - NM_182688
RefSeq Peptide - NP_001189418
RefSeq Peptide - NP_003334
RefSeq Peptide - NP_872630
swissprot - F8WCB9
swissprot - F8WDB1
swissprot - P60604
Ensembl - ENSG00000184787
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2g2ENSDARG00000025404Danio rerio
 UBE2G2ENSGALG00000005667Gallus gallus
 P60605ENSMUSG00000009293Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P62253 / UBE2G1 / ubiquitin conjugating enzyme E2 G1ENSG0000013238848
Q712K3 / UBE2R2 / ubiquitin conjugating enzyme E2 R2ENSG0000010734147
CDC34 / P49427 / cell division cycle 34ENSG0000009980446


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process TAS
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IMP
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0035458 cellular response to interferon-beta IMP
 biological_processGO:0044257 cellular protein catabolic process IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:1904153 negative regulation of retrograde protein transport, ER to cytosol IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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