ENSG00000132388


Homo sapiens

Features
Gene ID: ENSG00000132388
  
Biological name :UBE2G1
  
Synonyms : P62253 / UBE2G1 / ubiquitin conjugating enzyme E2 G1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 4269259
Gene end: 4366628
  
Corresponding Affymetrix probe sets: 209141_at (Human Genome U133 Plus 2.0 Array)   209142_s_at (Human Genome U133 Plus 2.0 Array)   226005_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458253
Ensembl peptide - ENSP00000459847
Ensembl peptide - ENSP00000380178
Ensembl peptide - ENSP00000467502
Ensembl peptide - ENSP00000459485
Ensembl peptide - ENSP00000459691
NCBI entrez gene - 7326     See in Manteia.
OMIM - 601569
RefSeq - NM_003342
RefSeq Peptide - NP_003333
swissprot - I3L2Q4
swissprot - I3L0Q0
swissprot - P62253
swissprot - K7EPR7
swissprot - I3L2H7
Ensembl - ENSG00000132388
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2g1aENSDARG00000015292Danio rerio
 UBE2G1ENSGALG00000001441Gallus gallus
 P62254ENSMUSG00000020794Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q712K3 / UBE2R2 / ubiquitin conjugating enzyme E2 R2ENSG0000010734151
CDC34 / P49427 / cell division cycle 34ENSG0000009980449
P60604 / UBE2G2 / ubiquitin conjugating enzyme E2 G2ENSG0000018478747


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process TAS
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0044257 cellular protein catabolic process IMP
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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