ENSG00000108559


Homo sapiens

Features
Gene ID: ENSG00000108559
  
Biological name :NUP88
  
Synonyms : nucleoporin 88 / NUP88 / Q99567
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 5360963
Gene end: 5420160
  
Corresponding Affymetrix probe sets: 202900_s_at (Human Genome U133 Plus 2.0 Array)   214192_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458954
Ensembl peptide - ENSP00000459979
Ensembl peptide - ENSP00000461334
Ensembl peptide - ENSP00000225696
Ensembl peptide - ENSP00000459370
NCBI entrez gene - 4927     See in Manteia.
OMIM - 602552
RefSeq - XM_017024694
RefSeq - NM_001320653
RefSeq - NM_002532
RefSeq - XM_011523893
RefSeq Peptide - NP_002523
RefSeq Peptide - NP_001307582
swissprot - J3KMX1
swissprot - Q99567
swissprot - I3L2W3
swissprot - I3L4K7
swissprot - I3L245
Ensembl - ENSG00000108559
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup88ENSDARG00000003235Danio rerio
 NUP88ENSGALG00000032280Gallus gallus
 Nup88ENSMUSG00000040667Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR019321  Nucleoporin Nup88


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000055 ribosomal large subunit export from nucleus IEA
 biological_processGO:0000056 ribosomal small subunit export from nucleus IEA
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005215 transporter activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017056 structural constituent of nuclear pore IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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