ENSG00000108849


Homo sapiens

Features
Gene ID: ENSG00000108849
  
Biological name :PPY
  
Synonyms : P01298 / pancreatic polypeptide / PPY
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.31
Gene start: 43940804
Gene end: 43942468
  
Corresponding Affymetrix probe sets: 210670_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000225992
Ensembl peptide - ENSP00000466009
Ensembl peptide - ENSP00000466546
Ensembl peptide - ENSP00000489472
Ensembl peptide - ENSP00000465711
NCBI entrez gene - 5539     See in Manteia.
OMIM - 167780
RefSeq - XM_011524978
RefSeq - NM_001319209
RefSeq - NM_002722
RefSeq Peptide - NP_001306138
RefSeq Peptide - NP_002713
swissprot - P01298
swissprot - A0A0U1RRD5
swissprot - K7EKP2
swissprot - K7EML0
Ensembl - ENSG00000108849
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PpyENSMUSG00000017316Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001955  Pancreatic hormone-like
 IPR015480  Pancreatic hormone
 IPR020392  Pancreatic hormone-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007631 feeding behavior IBA
 biological_processGO:0009306 protein secretion TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032098 regulation of appetite IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164129 NPY5R / Q15761 / neuropeptide Y receptor Y5  / complex / reaction
 ENSG00000204174 NPY4R / P50391 / neuropeptide Y receptor Y4  / reaction / complex
 ENSG00000164128 NPY1R / P25929 / neuropeptide Y receptor Y1  / reaction / complex
 ENSG00000185149 NPY2R / P49146 / neuropeptide Y receptor Y2  / reaction / complex






 

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