ENSG00000164128


Homo sapiens

Features
Gene ID: ENSG00000164128
  
Biological name :NPY1R
  
Synonyms : neuropeptide Y receptor Y1 / NPY1R / P25929
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q32.2
Gene start: 163323961
Gene end: 163344832
  
Corresponding Affymetrix probe sets: 205440_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421618
Ensembl peptide - ENSP00000354652
Ensembl peptide - ENSP00000427564
Ensembl peptide - ENSP00000427284
Ensembl peptide - ENSP00000426099
Ensembl peptide - ENSP00000423878
Ensembl peptide - ENSP00000422963
NCBI entrez gene - 4886     See in Manteia.
OMIM - 162641
RefSeq - NM_000909
RefSeq - XM_005263031
RefSeq - XM_011532010
RefSeq Peptide - NP_000900
swissprot - D6R9D0
swissprot - D6RI97
swissprot - P25929
swissprot - B4DKL9
swissprot - D6RHH6
swissprot - D6REY0
swissprot - D6RC44
Ensembl - ENSG00000164128
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 npy1rENSDARG00000037411Danio rerio
 NPY1RENSGALG00000009498Gallus gallus
 Npy1rENSMUSG00000036437Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPY4R / P50391 / neuropeptide Y receptor Y4ENSG0000020417443
NPY4R2 / neuropeptide Y receptor Y4-2ENSG0000026471743
NPY5R / Q15761 / neuropeptide Y receptor Y5ENSG0000016412929
NPY2R / P49146 / neuropeptide Y receptor Y2ENSG0000018514927
PRLHR / P49683 / prolactin releasing hormone receptorENSG0000011997326
GPR83 / Q9NYM4 / G protein-coupled receptor 83ENSG0000012390126
TACR2 / P21452 / tachykinin receptor 2ENSG0000007507326
TACR3 / P29371 / tachykinin receptor 3ENSG0000016983626
TACR1 / P25103 / tachykinin receptor 1ENSG0000011535325
PROKR2 / Q8NFJ6 / prokineticin receptor 2ENSG0000010129221
PROKR1 / Q8TCW9 / prokineticin receptor 1ENSG0000016961821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000351  Neuropeptide Y1 receptor
 IPR000611  Neuropeptide Y receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0008015 blood circulation IBA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001601 peptide YY receptor activity IEA
 molecular_functionGO:0001602 pancreatic polypeptide receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004983 neuropeptide Y receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108849 PPY / P01298 / pancreatic polypeptide  / reaction / complex
 ENSG00000122585 NPY / P01303 / neuropeptide Y  / reaction / complex
 ENSG00000131096 PYY / P10082 / peptide YY  / complex / reaction






 

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