ENSG00000164129


Homo sapiens

Features
Gene ID: ENSG00000164129
  
Biological name :NPY5R
  
Synonyms : neuropeptide Y receptor Y5 / NPY5R / Q15761
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q32.2
Gene start: 163343939
Gene end: 163351934
  
Corresponding Affymetrix probe sets: 207400_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000339377
Ensembl peptide - ENSP00000423474
Ensembl peptide - ENSP00000423917
NCBI entrez gene - 4889     See in Manteia.
OMIM - 602001
RefSeq - XM_017008255
RefSeq - NM_001317091
RefSeq - NM_001317092
RefSeq - NM_006174
RefSeq - XM_005263038
RefSeq - XM_011532015
RefSeq - XM_011532017
RefSeq Peptide - NP_001304020
RefSeq Peptide - NP_001304021
RefSeq Peptide - NP_006165
swissprot - Q15761
Ensembl - ENSG00000164129
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPY5RENSGALG00000009499Gallus gallus
 Npy5rENSMUSG00000044014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPY1R / P25929 / neuropeptide Y receptor Y1ENSG0000016412825
PRLHR / P49683 / prolactin releasing hormone receptorENSG0000011997324
NPY4R / P50391 / neuropeptide Y receptor Y4ENSG0000020417423
NPY2R / P49146 / neuropeptide Y receptor Y2ENSG0000018514923
NPY4R2 / neuropeptide Y receptor Y4-2ENSG0000026471723
GPR83 / Q9NYM4 / G protein-coupled receptor 83ENSG0000012390120
PROKR1 / Q8TCW9 / prokineticin receptor 1ENSG0000016961818
PROKR2 / Q8NFJ6 / prokineticin receptor 2ENSG0000010129218
TACR2 / P21452 / tachykinin receptor 2ENSG0000007507317
TACR3 / P29371 / tachykinin receptor 3ENSG0000016983617
TACR1 / P25103 / tachykinin receptor 1ENSG0000011535317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000393  Neuropeptide Y5 receptor
 IPR000611  Neuropeptide Y receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002675 positive regulation of acute inflammatory response IEA
 biological_processGO:0002865 negative regulation of acute inflammatory response to antigenic stimulus IEA
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0003214 cardiac left ventricle morphogenesis IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007631 feeding behavior IBA
 biological_processGO:0008015 blood circulation IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0014050 negative regulation of glutamate secretion IEA
 biological_processGO:0032229 negative regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0060112 generation of ovulation cycle rhythm IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0001601 peptide YY receptor activity IEA
 molecular_functionGO:0001602 pancreatic polypeptide receptor activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004983 neuropeptide Y receptor activity TAS


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108849 PPY / P01298 / pancreatic polypeptide  / complex / reaction
 ENSG00000122585 NPY / P01303 / neuropeptide Y  / complex / reaction
 ENSG00000131096 PYY / P10082 / peptide YY  / reaction / complex






 

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