ENSG00000109674


Homo sapiens

Features
Gene ID: ENSG00000109674
  
Biological name :NEIL3
  
Synonyms : NEIL3 / nei like DNA glycosylase 3 / Q8TAT5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q34.3
Gene start: 177309836
Gene end: 177362943
  
Corresponding Affymetrix probe sets: 219502_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264596
Ensembl peptide - ENSP00000424735
NCBI entrez gene - 55247     See in Manteia.
OMIM - 608934
RefSeq - NM_018248
RefSeq - XM_017008360
RefSeq Peptide - NP_060718
swissprot - D6RAV1
swissprot - Q8TAT5
Ensembl - ENSG00000109674
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neil3ENSDARG00000020079Danio rerio
 Neil3ENSMUSG00000039396Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEIL2 / Q969S2 / nei like DNA glycosylase 2ENSG0000015432810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000214  Zinc finger, DNA glycosylase/AP lyase-type
 IPR001876  Zinc finger, RanBP2-type
 IPR010666  Zinc finger, GRF-type
 IPR010979  Ribosomal protein S13-like, H2TH
 IPR012319  Formamidopyrimidine-DNA glycosylase, catalytic domain
 IPR015886  DNA glycosylase/AP lyase, H2TH DNA-binding
 IPR015887  DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site
 IPR035937  MutM-like, N-terminal
 IPR036443  Zinc finger, RanBP2-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006284 base-excision repair IDA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000405 bubble DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0019104 DNA N-glycosylase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
 molecular_functionGO:0140080 class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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