ENSG00000109814


Homo sapiens

Features
Gene ID: ENSG00000109814
  
Biological name :UGDH
  
Synonyms : O60701 / UDP-glucose 6-dehydrogenase / UGDH
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p14
Gene start: 39498755
Gene end: 39528311
  
Corresponding Affymetrix probe sets: 203343_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422565
Ensembl peptide - ENSP00000422603
Ensembl peptide - ENSP00000427708
Ensembl peptide - ENSP00000426560
Ensembl peptide - ENSP00000425834
Ensembl peptide - ENSP00000424435
Ensembl peptide - ENSP00000424059
Ensembl peptide - ENSP00000422909
Ensembl peptide - ENSP00000319501
Ensembl peptide - ENSP00000421757
Ensembl peptide - ENSP00000421954
NCBI entrez gene - 7358     See in Manteia.
OMIM - 603370
RefSeq - XM_005262667
RefSeq - NM_001184700
RefSeq - NM_001184701
RefSeq - NM_003359
RefSeq Peptide - NP_003350
RefSeq Peptide - NP_001171629
RefSeq Peptide - NP_001171630
swissprot - E9PBD2
swissprot - E7EV97
swissprot - E7ETF4
swissprot - E7ER83
swissprot - E7ER95
swissprot - D6RHF4
swissprot - O60701
Ensembl - ENSG00000109814
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ugdhENSDARG00000019838Danio rerio
 UGDHENSGALG00000041993Gallus gallus
 UgdhENSMUSG00000029201Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001732  UDP-glucose/GDP-mannose dehydrogenase, N-terminal
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR014026  UDP-glucose/GDP-mannose dehydrogenase, dimerisation
 IPR014027  UDP-glucose/GDP-mannose dehydrogenase, C-terminal
 IPR017476  UDP-glucose/GDP-mannose dehydrogenase
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR028356  UDP-glucose 6-dehydrogenase, eukaryotic type
 IPR036220  UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0006011 UDP-glucose metabolic process TAS
 biological_processGO:0006024 glycosaminoglycan biosynthetic process TAS
 biological_processGO:0006065 UDP-glucuronate biosynthetic process TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003979 UDP-glucose 6-dehydrogenase activity TAS
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Formation of the active cofactor, UDP-glucuronate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109814 UGDH / O60701 / UDP-glucose 6-dehydrogenase  / complex






 

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