ENSG00000110693


Homo sapiens

Features
Gene ID: ENSG00000110693
  
Biological name :SOX6
  
Synonyms : P35712 / SOX6 / SRY-box 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.2
Gene start: 15966449
Gene end: 16739591
  
Corresponding Affymetrix probe sets: 1563454_at (Human Genome U133 Plus 2.0 Array)   1570486_at (Human Genome U133 Plus 2.0 Array)   223865_at (Human Genome U133 Plus 2.0 Array)   224178_s_at (Human Genome U133 Plus 2.0 Array)   227497_at (Human Genome U133 Plus 2.0 Array)   227498_at (Human Genome U133 Plus 2.0 Array)   228214_at (Human Genome U133 Plus 2.0 Array)   235526_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432577
Ensembl peptide - ENSP00000436170
Ensembl peptide - ENSP00000434892
Ensembl peptide - ENSP00000434455
Ensembl peptide - ENSP00000433233
Ensembl peptide - ENSP00000432596
Ensembl peptide - ENSP00000324948
Ensembl peptide - ENSP00000379644
Ensembl peptide - ENSP00000432134
NCBI entrez gene - 55553     See in Manteia.
OMIM - 607257
RefSeq - NM_033326
RefSeq - NM_001145811
RefSeq - NM_001145819
RefSeq - NM_017508
RefSeq Peptide - NP_001139283
RefSeq Peptide - NP_059978
RefSeq Peptide - NP_201583
RefSeq Peptide - NP_001139291
swissprot - P35712
swissprot - E9PQ78
swissprot - E9PQ67
swissprot - E9PN02
swissprot - E9PQL4
Ensembl - ENSG00000110693
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox6ENSDARG00000015536Danio rerio
 SOX6ENSGALG00000006074Gallus gallus
 Sox6ENSMUSG00000051910Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOX5 / P35711 / SRY-box 5ENSG0000013453258
SOX13 / Q9UN79 / SRY-box 13ENSG0000014384233
SOX30 / O94993 / SRY-box 30ENSG0000003960014


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR027153  Transcription factor SOX-6
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development NAS
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0016458 gene silencing IEA
 biological_processGO:0021778 oligodendrocyte cell fate specification IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IEA
 biological_processGO:0042692 muscle cell differentiation IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048708 astrocyte differentiation IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0048821 erythrocyte development IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 biological_processGO:0061036 positive regulation of cartilage development IDA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IDA
 biological_processGO:2000726 negative regulation of cardiac muscle cell differentiation IMP
 biological_processGO:2000741 positive regulation of mesenchymal stem cell differentiation IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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