ENSG00000112245


Homo sapiens

Features
Gene ID: ENSG00000112245
  
Biological name :PTP4A1
  
Synonyms : protein tyrosine phosphatase type IVA, member 1 / PTP4A1 / Q93096
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q12
Gene start: 63521748
Gene end: 63583587
  
Corresponding Affymetrix probe sets: 200730_s_at (Human Genome U133 Plus 2.0 Array)   200731_s_at (Human Genome U133 Plus 2.0 Array)   200732_s_at (Human Genome U133 Plus 2.0 Array)   200733_s_at (Human Genome U133 Plus 2.0 Array)   240329_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000485687
Ensembl peptide - ENSP00000487586
Ensembl peptide - ENSP00000359685
Ensembl peptide - ENSP00000462406
NCBI entrez gene - 7803     See in Manteia.
OMIM - 601585
RefSeq - XM_017011272
RefSeq - NM_003463
RefSeq - XM_011536111
RefSeq - XM_011536112
RefSeq - XM_017011270
RefSeq - XM_017011271
RefSeq Peptide - NP_003454
swissprot - A0A0D9SGK2
swissprot - J3KSB4
swissprot - A0A024R8J2
swissprot - Q93096
Ensembl - ENSG00000112245
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptp4a1ENSDARG00000006242Danio rerio
 PTP4A1ENSGALG00000016271Gallus gallus
 Ptp4a1ENSMUSG00000026064Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTP4A2 / Q12974 / protein tyrosine phosphatase type IVA, member 2ENSG0000018400785
O75365 / PTP4A3 / protein tyrosine phosphatase type IVA, member 3ENSG0000018448977


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030335 positive regulation of cell migration IBA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr