ENSG00000184007


Homo sapiens

Features
Gene ID: ENSG00000184007
  
Biological name :PTP4A2
  
Synonyms : protein tyrosine phosphatase type IVA, member 2 / PTP4A2 / Q12974
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.2
Gene start: 31906421
Gene end: 31944856
  
Corresponding Affymetrix probe sets: 208615_s_at (Human Genome U133 Plus 2.0 Array)   208616_s_at (Human Genome U133 Plus 2.0 Array)   208617_s_at (Human Genome U133 Plus 2.0 Array)   216988_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435941
Ensembl peptide - ENSP00000437251
Ensembl peptide - ENSP00000493688
Ensembl peptide - ENSP00000486246
Ensembl peptide - ENSP00000486151
Ensembl peptide - ENSP00000473490
Ensembl peptide - ENSP00000473259
Ensembl peptide - ENSP00000409260
Ensembl peptide - ENSP00000433050
Ensembl peptide - ENSP00000433375
Ensembl peptide - ENSP00000433800
NCBI entrez gene - 8073     See in Manteia.
OMIM - 601584
RefSeq - XM_017002401
RefSeq - NM_001195100
RefSeq - NM_001195101
RefSeq - NM_080391
RefSeq - XM_005271231
RefSeq - XM_005271232
RefSeq Peptide - NP_001182029
RefSeq Peptide - NP_001182030
RefSeq Peptide - NP_536316
swissprot - E9PML8
swissprot - E9PL34
swissprot - E9PJC0
swissprot - E9PMY3
swissprot - E9PRR9
swissprot - Q12974
Ensembl - ENSG00000184007
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptp4a2aENSDARG00000087443Danio rerio
 ptp4a2bENSDARG00000035676Danio rerio
 PTP4A2ENSGALG00000003265Gallus gallus
 O70274ENSMUSG00000028788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTP4A1 / Q93096 / protein tyrosine phosphatase type IVA, member 1ENSG0000011224588
O75365 / PTP4A3 / protein tyrosine phosphatase type IVA, member 3ENSG0000018448977


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0004727 prenylated protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137955 P53611 / RABGGTB / Rab geranylgeranyltransferase beta subunit  / reaction / complex






 

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