ENSG00000113657


Homo sapiens

Features
Gene ID: ENSG00000113657
  
Biological name :DPYSL3
  
Synonyms : dihydropyrimidinase like 3 / DPYSL3 / Q14195
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q32
Gene start: 147390811
Gene end: 147510056
  
Corresponding Affymetrix probe sets: 201430_s_at (Human Genome U133 Plus 2.0 Array)   201431_s_at (Human Genome U133 Plus 2.0 Array)   237292_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381526
Ensembl peptide - ENSP00000430267
Ensembl peptide - ENSP00000428958
Ensembl peptide - ENSP00000426720
Ensembl peptide - ENSP00000343690
NCBI entrez gene - 1809     See in Manteia.
OMIM - 601168
RefSeq - XM_011537574
RefSeq - NM_001197294
RefSeq - NM_001387
RefSeq Peptide - NP_001184223
RefSeq Peptide - NP_001378
swissprot - D6RF19
swissprot - H0YBT4
swissprot - H0YB87
swissprot - A0A140VK07
swissprot - Q14195
Ensembl - ENSG00000113657
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpysl3ENSDARG00000002587Danio rerio
 DPYSL3ENSGALG00000007582Gallus gallus
 Dpysl3ENSMUSG00000024501Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRMP1 / Q14194 / collapsin response mediator protein 1ENSG0000007283269
DPYSL2 / Q16555 / dihydropyrimidinase like 2ENSG0000009296467
DPYSL4 / O14531 / dihydropyrimidinase like 4ENSG0000015164058
DPYS / Q14117 / dihydropyrimidinaseENSG0000014764745
DPYSL5 / Q9BPU6 / dihydropyrimidinase like 5ENSG0000015785142


Protein motifs (from Interpro)
Interpro ID Name
 IPR006680  Amidohydrolase-related
 IPR011059  Metal-dependent hydrolase, composite domain superfamily
 IPR011778  Hydantoinase/dihydropyrimidinase
 IPR030628  Dihydropyrimidinase-related protein 3
 IPR032466  Metal-dependent hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010975 regulation of neuron projection development IEA
 biological_processGO:0010976 positive regulation of neuron projection development ISS
 biological_processGO:0010977 negative regulation of neuron projection development ISS
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0030336 negative regulation of cell migration ISS
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051260 protein homooligomerization ISS
 biological_processGO:0051491 positive regulation of filopodium assembly IEA
 biological_processGO:0051764 actin crosslink formation ISS
 biological_processGO:0071345 cellular response to cytokine stimulus ISS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0031941 filamentous actin ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0044297 cell body ISS
 cellular_componentGO:0070382 exocytic vesicle ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA
 molecular_functionGO:0017124 SH3 domain binding ISS
 molecular_functionGO:0031005 filamin binding IPI
 molecular_functionGO:0035374 chondroitin sulfate binding ISS


Pathways (from Reactome)
Pathway description
CRMPs in Sema3A signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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