ENSG00000114125


Homo sapiens

Features
Gene ID: ENSG00000114125
  
Biological name :RNF7
  
Synonyms : Q9UBF6 / ring finger protein 7 / RNF7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q23
Gene start: 141738204
Gene end: 141747560
  
Corresponding Affymetrix probe sets: 218286_s_at (Human Genome U133 Plus 2.0 Array)   224394_at (Human Genome U133 Plus 2.0 Array)   224395_s_at (Human Genome U133 Plus 2.0 Array)   224439_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376725
Ensembl peptide - ENSP00000419339
Ensembl peptide - ENSP00000419979
Ensembl peptide - ENSP00000273480
Ensembl peptide - ENSP00000419084
NCBI entrez gene - 9616     See in Manteia.
OMIM - 603863
RefSeq - NM_014245
RefSeq - NM_001201370
RefSeq - NM_183237
RefSeq Peptide - NP_055060
RefSeq Peptide - NP_001188299
RefSeq Peptide - NP_899060
swissprot - Q9UBF6
swissprot - F8WEU8
Ensembl - ENSG00000114125
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf7ENSDARG00000055524Danio rerio
 RNF7ENSGALG00000021117Gallus gallus
 Gm7075ENSMUSG00000048185Mus musculus
 Rnf7ENSMUSG00000051234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RBX1 / P62877 / ring-box 1ENSG0000010038745


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR024766  Zinc finger, RING-H2-type
 IPR024991  Anaphase-promoting complex subunit 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045116 protein neddylation IDA
 biological_processGO:0051775 response to redox state TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex IBA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 cellular_componentGO:0031466 Cul5-RING ubiquitin ligase complex IDA
 cellular_componentGO:0031467 Cul7-RING ubiquitin ligase complex IBA
 cellular_componentGO:0043224 nuclear SCF ubiquitin ligase complex IBA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005507 copper ion binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0019788 NEDD8 transferase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0097602 cullin family protein binding IDA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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