ENSG00000115421


Homo sapiens

Features
Gene ID: ENSG00000115421
  
Biological name :PAPOLG
  
Synonyms : PAPOLG / poly(A) polymerase gamma / Q9BWT3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p16.1
Gene start: 60756230
Gene end: 60802085
  
Corresponding Affymetrix probe sets: 1556929_at (Human Genome U133 Plus 2.0 Array)   219160_s_at (Human Genome U133 Plus 2.0 Array)   222273_at (Human Genome U133 Plus 2.0 Array)   222839_s_at (Human Genome U133 Plus 2.0 Array)   224427_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414070
Ensembl peptide - ENSP00000238714
Ensembl peptide - ENSP00000405570
Ensembl peptide - ENSP00000405599
NCBI entrez gene - 64895     See in Manteia.
OMIM - 616865
RefSeq - XM_017004724
RefSeq - NM_022894
RefSeq - XM_005264500
RefSeq - XM_005264501
RefSeq - XM_011533041
RefSeq - XM_017004723
RefSeq Peptide - NP_075045
swissprot - F8WAT4
swissprot - H7C3W0
swissprot - A0A0C4DH56
swissprot - Q9BWT3
Ensembl - ENSG00000115421
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 papolgENSDARG00000012141Danio rerio
 PAPOLGENSGALG00000007853Gallus gallus
 PapolgENSMUSG00000020273Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P51003 / PAPOLA / poly(A) polymerase alphaENSG0000009006057
PAPOLB / Q9NRJ5 / poly(A) polymerase betaENSG0000021882350


Protein motifs (from Interpro)
Interpro ID Name
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR007010  Poly(A) polymerase, RNA-binding domain
 IPR007012  Poly(A) polymerase, central domain
 IPR011068  Nucleotidyltransferase, class I-like, C-terminal
 IPR014492  Poly(A) polymerase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0031123 RNA 3"-end processing IEA
 biological_processGO:0043631 RNA polyadenylation IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004652 polynucleotide adenylyltransferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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