ENSG00000218823


Homo sapiens

Features
Gene ID: ENSG00000218823
  
Biological name :PAPOLB
  
Synonyms : PAPOLB / poly(A) polymerase beta / Q9NRJ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p22.1
Gene start: 4857733
Gene end: 4861994
  
Corresponding Affymetrix probe sets: 208271_at (Human Genome U133 Plus 2.0 Array)   242158_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384700
NCBI entrez gene - 56903     See in Manteia.
OMIM - 607436
RefSeq - NM_020144
RefSeq Peptide - NP_064529
swissprot - A4D1Z6
swissprot - Q9NRJ5
Ensembl - ENSG00000218823
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 papolaENSDARG00000009585Danio rerio
 PAPOLAENSGALG00000033099Gallus gallus
 PapolbENSMUSG00000074817Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P51003 / PAPOLA / poly(A) polymerase alphaENSG0000009006084
PAPOLG / Q9BWT3 / poly(A) polymerase gammaENSG0000011542158


Protein motifs (from Interpro)
Interpro ID Name
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR007010  Poly(A) polymerase, RNA-binding domain
 IPR007012  Poly(A) polymerase, central domain
 IPR011068  Nucleotidyltransferase, class I-like, C-terminal
 IPR014492  Poly(A) polymerase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0031123 RNA 3"-end processing IEA
 biological_processGO:0043631 RNA polyadenylation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004652 polynucleotide adenylyltransferase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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