ENSG00000116731


Homo sapiens

Features
Gene ID: ENSG00000116731
  
Biological name :PRDM2
  
Synonyms : PRDM2 / PR/SET domain 2 / Q13029
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.21
Gene start: 13700198
Gene end: 13825079
  
Corresponding Affymetrix probe sets: 203056_s_at (Human Genome U133 Plus 2.0 Array)   203057_s_at (Human Genome U133 Plus 2.0 Array)   205277_at (Human Genome U133 Plus 2.0 Array)   216433_s_at (Human Genome U133 Plus 2.0 Array)   216445_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424253
Ensembl peptide - ENSP00000423010
Ensembl peptide - ENSP00000425028
Ensembl peptide - ENSP00000474273
Ensembl peptide - ENSP00000426737
Ensembl peptide - ENSP00000235372
Ensembl peptide - ENSP00000312352
Ensembl peptide - ENSP00000341621
Ensembl peptide - ENSP00000365216
Ensembl peptide - ENSP00000384430
Ensembl peptide - ENSP00000411103
NCBI entrez gene - 7799     See in Manteia.
OMIM - 601196
RefSeq - XM_017002264
RefSeq - NM_012231
RefSeq - NM_015866
RefSeq - XM_017002253
RefSeq - XM_017002254
RefSeq - XM_017002255
RefSeq - XM_017002256
RefSeq - XM_017002257
RefSeq - XM_017002258
RefSeq - XM_017002259
RefSeq - XM_017002262
RefSeq - NM_001007257
RefSeq - NM_001135610
RefSeq Peptide - NP_056950
RefSeq Peptide - NP_001007258
RefSeq Peptide - NP_001129082
RefSeq Peptide - NP_036363
swissprot - D6RJM6
swissprot - D6RAA0
swissprot - S4R3F7
swissprot - D6RED5
swissprot - H0Y9J3
swissprot - Q13029
Ensembl - ENSG00000116731
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prdm2aENSDARG00000090721Danio rerio
 prdm2bENSDARG00000076451Danio rerio
 PRDM2ENSGALG00000038780Gallus gallus
 Prdm2ENSMUSG00000057637Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRDM7 / Q9NQW5 / PR/SET domain 7ENSG000001268564


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR009170  Predicted retinoblastoma binding protein (RIZ)
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008340 determination of adult lifespan IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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