ENSG00000116990


Homo sapiens

Features
Gene ID: ENSG00000116990
  
Biological name :MYCL
  
Synonyms : MYCL / MYCL proto-oncogene, bHLH transcription factor / P12524
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.2
Gene start: 39895426
Gene end: 39902256
  
Corresponding Affymetrix probe sets: 214058_at (Human Genome U133 Plus 2.0 Array)   215491_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434375
Ensembl peptide - ENSP00000361902
Ensembl peptide - ENSP00000361903
Ensembl peptide - ENSP00000380494
NCBI entrez gene - 4610     See in Manteia.
OMIM - 164850
RefSeq - NM_001033081
RefSeq - NM_001033082
RefSeq - NM_005376
RefSeq Peptide - NP_001028253
RefSeq Peptide - NP_001028254
RefSeq Peptide - NP_005367
swissprot - P12524
swissprot - E9PQS5
Ensembl - ENSG00000116990
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myclaENSDARG00000006003Danio rerio
 myclbENSDARG00000034956Danio rerio
 MYCLENSGALG00000024047Gallus gallus
 MyclENSMUSG00000028654Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYCN / P04198 / MYCN proto-oncogene, bHLH transcription factorENSG0000013432333
MYC / P01106 / MYC proto-oncogene, bHLH transcription factorENSG0000013699727


Protein motifs (from Interpro)
Interpro ID Name
 IPR002418  Transcription regulator Myc
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR012682  Transcription regulator Myc, N-terminal
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045607 regulation of inner ear auditory receptor cell differentiation IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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