ENSG00000118160


Homo sapiens

Features
Gene ID: ENSG00000118160
  
Biological name :SLC8A2
  
Synonyms : Q9UPR5 / SLC8A2 / solute carrier family 8 member A2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.32
Gene start: 47428017
Gene end: 47472168
  
Corresponding Affymetrix probe sets: 215267_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000236877
Ensembl peptide - ENSP00000437536
Ensembl peptide - ENSP00000472208
Ensembl peptide - ENSP00000472233
NCBI entrez gene - 6543     See in Manteia.
OMIM - 601901
RefSeq - XM_017027159
RefSeq - NM_015063
RefSeq - XM_005259172
RefSeq Peptide - NP_055878
swissprot - F5H6L7
swissprot - Q9UPR5
swissprot - M0R1Z4
swissprot - M0R211
Ensembl - ENSG00000118160
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc8a2aENSDARG00000008912Danio rerio
 slc8a2bENSDARG00000100592Danio rerio
 Q8K596ENSMUSG00000030376Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P57103 / SLC8A3 / solute carrier family 8 member A3ENSG0000010067870
P32418 / SLC8A1 / solute carrier family 8 member A1ENSG0000018302367
ADGRV1 / Q8WXG9 / adhesion G protein-coupled receptor V1ENSG0000016419928


Protein motifs (from Interpro)
Interpro ID Name
 IPR003644  Na-Ca exchanger/integrin-beta4
 IPR004836  Sodium/calcium exchanger protein
 IPR004837  Sodium/calcium exchanger membrane region
 IPR032452  Sodium/calcium exchanger domain, C-terminal extension


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0048172 regulation of short-term neuronal synaptic plasticity IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:1903779 regulation of cardiac conduction TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005432 calcium:sodium antiporter activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reduction of cytosolic Ca++ levels
Sodium/Calcium exchangers
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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