ENSG00000120733


Homo sapiens

Features
Gene ID: ENSG00000120733
  
Biological name :KDM3B
  
Synonyms : KDM3B / lysine demethylase 3B / Q7LBC6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q31.2
Gene start: 138352596
Gene end: 138437028
  
Corresponding Affymetrix probe sets: 201643_x_at (Human Genome U133 Plus 2.0 Array)   210878_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000326563
Ensembl peptide - ENSP00000423012
Ensembl peptide - ENSP00000425186
Ensembl peptide - ENSP00000439462
NCBI entrez gene - 51780     See in Manteia.
OMIM - 609373
RefSeq - XM_017009584
RefSeq - NM_016604
RefSeq - XM_005272018
RefSeq - XM_011543488
RefSeq - XM_011543489
RefSeq Peptide - NP_057688
swissprot - H0Y9V5
swissprot - H0Y946
swissprot - Q7LBC6
Ensembl - ENSG00000120733
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kdm3bENSDARG00000062267Danio rerio
 KDM3BENSGALG00000007663Gallus gallus
 Kdm3bENSMUSG00000038773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
JMJD1C / Q15652 / jumonji domain containing 1CENSG0000017198837
KDM3A / Q9Y4C1 / lysine demethylase 3AENSG0000011554837
HR / O43593 / HR, lysine demethylase and nuclear receptor corepressorENSG0000016845314


Protein motifs (from Interpro)
Interpro ID Name
 IPR003347  JmjC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0033169 histone H3-K9 demethylation IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0072718 response to cisplatin IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0000785 chromatin IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0016209 antioxidant activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0031490 chromatin DNA binding IBA
 molecular_functionGO:0032452 histone demethylase activity TAS
 molecular_functionGO:0032454 histone demethylase activity (H3-K9 specific) IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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