ENSG00000121749


Homo sapiens

Features
Gene ID: ENSG00000121749
  
Biological name :TBC1D15
  
Synonyms : Q8TC07 / TBC1D15 / TBC1 domain family member 15
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q21.1
Gene start: 71839707
Gene end: 71927248
  
Corresponding Affymetrix probe sets: 218268_at (Human Genome U133 Plus 2.0 Array)   230072_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448182
Ensembl peptide - ENSP00000420678
Ensembl peptide - ENSP00000449643
Ensembl peptide - ENSP00000318262
Ensembl peptide - ENSP00000417308
Ensembl peptide - ENSP00000418091
Ensembl peptide - ENSP00000418467
Ensembl peptide - ENSP00000419365
Ensembl peptide - ENSP00000420190
NCBI entrez gene - 64786     See in Manteia.
OMIM - 612662
RefSeq - XM_017019828
RefSeq - XM_006719566
RefSeq - XM_006719567
RefSeq - XM_011538679
RefSeq - XM_011538680
RefSeq - XM_011538681
RefSeq - XM_011538682
RefSeq - XM_017019824
RefSeq - XM_017019825
RefSeq - XM_017019826
RefSeq - XM_017019827
RefSeq - NM_001146213
RefSeq - NM_001146214
RefSeq - NM_022771
RefSeq - XM_006719564
RefSeq - XM_006719565
RefSeq Peptide - NP_001139686
RefSeq Peptide - NP_073608
RefSeq Peptide - NP_001139685
swissprot - F8WDJ1
swissprot - F8WF35
swissprot - F8VV61
swissprot - Q8TC07
swissprot - C9JA93
swissprot - F8WAX5
swissprot - F8WCB5
Ensembl - ENSG00000121749
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d15ENSDARG00000057218Danio rerio
 TBC1D15ENSGALG00000010190Gallus gallus
 Q9CXF4ENSMUSG00000020130Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HA65 / TBC1D17 / TBC1 domain family member 17ENSG0000010494645
Q3MII6 / TBC1D25 / TBC1 domain family member 25ENSG0000006835423
Q8TBP0 / TBC1D16 / TBC1 domain family member 16ENSG0000016729123
SGSM2 / O43147 / small G protein signaling modulator 2ENSG0000014125822
SGSM1 / Q2NKQ1 / small G protein signaling modulator 1ENSG0000016703720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR021935  Domain of unknown function DUF3548
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0043087 regulation of GTPase activity ISS
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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