ENSG00000068354


Homo sapiens

Features
Gene ID: ENSG00000068354
  
Biological name :TBC1D25
  
Synonyms : Q3MII6 / TBC1D25 / TBC1 domain family member 25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p11.23
Gene start: 48539457
Gene end: 48562609
  
Corresponding Affymetrix probe sets: 226173_at (Human Genome U133 Plus 2.0 Array)   227820_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402268
Ensembl peptide - ENSP00000476787
Ensembl peptide - ENSP00000365962
NCBI entrez gene - 4943     See in Manteia.
OMIM - 311240
RefSeq - NM_001348263
RefSeq - NM_002536
RefSeq Peptide - NP_001335192
RefSeq Peptide - NP_002527
swissprot - C9JMI8
swissprot - Q3MII6
Ensembl - ENSG00000068354
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d25ENSDARG00000075333Danio rerio
 A1A5B6ENSMUSG00000039201Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HA65 / TBC1D17 / TBC1 domain family member 17ENSG0000010494623
Q8TC07 / TBC1D15 / TBC1 domain family member 15ENSG0000012174923
SGSM1 / Q2NKQ1 / small G protein signaling modulator 1ENSG0000016703720
Q8TBP0 / TBC1D16 / TBC1 domain family member 16ENSG0000016729119
SGSM2 / O43147 / small G protein signaling modulator 2ENSG0000014125819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 biological_processGO:1901096 regulation of autophagosome maturation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome TAS
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000140941 Q9GZQ8 / MAP1LC3B / microtubule associated protein 1 light chain 3 beta  / reaction / complex
 ENSG00000170296 O95166 / GABARAP / GABA type A receptor-associated protein  / reaction / complex
 ENSG00000034713 P60520 / GABARAPL2 / GABA type A receptor associated protein like 2  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr