ENSG00000034713


Homo sapiens

Features
Gene ID: ENSG00000034713
  
Biological name :GABARAPL2
  
Synonyms : GABARAPL2 / GABA type A receptor associated protein like 2 / P60520
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q23.1
Gene start: 75566351
Gene end: 75577881
  
Corresponding Affymetrix probe sets: 209046_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000037243
Ensembl peptide - ENSP00000456773
Ensembl peptide - ENSP00000457448
Ensembl peptide - ENSP00000455606
NCBI entrez gene - 11345     See in Manteia.
OMIM - 607452
RefSeq - NM_007285
RefSeq Peptide - NP_009216
swissprot - P60520
swissprot - H3BQ50
swissprot - H3BSM5
swissprot - H3BU36
Ensembl - ENSG00000034713
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabarapl2ENSDARG00000027200Danio rerio
 GABARAPL2ENSGALG00000003208Gallus gallus
 P60521ENSMUSG00000031950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H0R8 / GABARAPL1 / GABA type A receptor associated protein like 1ENSG0000013911261
O95166 / GABARAP / GABA type A receptor-associated proteinENSG0000017029657
Q9BXW4 / MAP1LC3C / microtubule associated protein 1 light chain 3 gammaENSG0000019776942
A6NCE7 / MAP1LC3B2 / microtubule associated protein 1 light chain 3 beta 2ENSG0000025810238
Q9GZQ8 / MAP1LC3B / microtubule associated protein 1 light chain 3 betaENSG0000014094138
Q9H492 / MAP1LC3A / microtubule associated protein 1 light chain 3 alphaENSG0000010146037


Protein motifs (from Interpro)
Interpro ID Name
 IPR004241  Autophagy protein Atg8 ubiquitin-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport ISS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0032781 positive regulation of ATPase activity ISS
 biological_processGO:0097352 autophagosome maturation TAS
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane TAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0000149 SNARE binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding NAS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0048487 beta-tubulin binding ISS
 molecular_functionGO:0050811 GABA receptor binding NAS
 molecular_functionGO:0051117 ATPase binding ISS


Pathways (from Reactome)
Pathway description
Macroautophagy
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000068354 Q3MII6 / TBC1D25 / TBC1 domain family member 25  / complex / reaction






 

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